Paper Details
- Home
- Paper Details
Effects of cevimeline on the immunolocalization of aquaporin-5 and the ultrastructure of salivary glands in Sjögren's syndrome model mice.
Author: NishimuraHidehiko, SagaTsuyoshi, YakeishiAkira, YamakiKoh-Ichi
Original Abstract of the Article :
Sjögren's syndrome (SS) is an autoimmune disorder whose main symptoms include xerostomia and dry eyes. It has been demonstrated that abnormal expression of aquaporin (AQP)-5 in the parotid and submandibular glands in SS model mice was corrected by cevimeline. In the present study, we orally administ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.2739/kurumemedj.56.39
データ提供:米国国立医学図書館(NLM)
Cevimeline: A Potential Oasis for Sjögren's Syndrome
Sjögren’s syndrome (SS), a chronic autoimmune disorder, can feel like traversing a dry and desolate desert, causing debilitating dryness of the mouth and eyes. Researchers are constantly searching for new ways to alleviate these symptoms and improve the quality of life for those affected by SS.
This study, like a group of explorers searching for a source of water in the desert, investigated the potential of cevimeline, a medication used to stimulate saliva production, to improve salivary gland function in mice with SS. Their findings revealed that cevimeline, like a refreshing oasis in the desert, could potentially improve salivary gland function in SS. They observed that cevimeline normalized the expression of aquaporin-5, a protein involved in water transport, and enhanced salivary gland secretion. This research offers a glimmer of hope for those seeking relief from the dryness and discomfort associated with SS.
A Glimmer of Hope: Cevimeline for Sjögren's Syndrome
This study suggests that cevimeline could offer a potential solution for improving salivary gland function in SS. The researchers’ findings highlight the importance of understanding the role of aquaporin-5 in salivary gland function and exploring strategies to restore its expression in SS.
Finding Relief in the Desert: Managing Sjögren's Syndrome
This research offers a ray of hope for those suffering from the debilitating dryness associated with SS. The researchers’ findings suggest that cevimeline could potentially alleviate these symptoms, improving the quality of life for those affected by this challenging condition. Further research is needed to investigate the long-term effects of cevimeline and to develop more effective treatments for SS.
Dr.Camel's Conclusion
This study highlights the potential of cevimeline to improve salivary gland function in SS. The researchers’ findings offer a glimmer of hope for those seeking relief from the dryness and discomfort associated with this chronic autoimmune disorder.
Date :
- Date Completed 2010-09-01
- Date Revised 2019-09-23
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.