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Antiretroviral regimens for patients with HIV who fail first-line antiretroviral therapy.

Author: ChangLarry W, HarrisJamal, HumphreysEliza H

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Treatment with highly active antiretroviral therapy (HAART) has significantly reduced illness and death in people with HIV/AIDS. A common initial HAART regimen in low-resource settings includes a non-nucleoside reverse transcriptase inhibitor (NNRTI) and two nucleoside reverse transcriptase inhibitors (NRTIs). When this treatment fails, a change to a second-line therapy is necessary.
Paper Details　
Original Abstract of the Article :
Highly active antiretroviral therapy has reduced the morbidity and mortality of patients with HIV/AIDS. A common first-line ART regimen in low-resource settings includes a non-nucleoside reverse transcriptase inhibitor (NNRTI) and two nucleoside reverse transcriptase inhibitors (NRTIs). If treatment...See full text at original site
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引用元：
https://doi.org/10.1002/14651858.CD006517.pub3

データ提供：米国国立医学図書館（NLM）

Navigating Treatment Failure in HIV: Exploring Second-Line Antiretroviral Regimens

The fight against HIV infection is a continuous journey, often requiring adjustments to treatment strategies when initial therapies fail. This study delves into the complex world of second-line antiretroviral therapy (ART), focusing on regimens for patients who experience treatment failure with first-line regimens. The study aims to provide guidance for clinicians in selecting effective second-line regimens, much like a camel navigating a challenging desert landscape, seeking a new path towards optimal treatment outcomes.

A Shifting Landscape: Navigating Treatment Failure in HIV

The study provides insights into the use of second-line ART regimens for patients with HIV who experience treatment failure with first-line therapies. This research, like a camel adapting to a changing desert environment, highlights the importance of flexibility and adaptability in managing HIV infection. The study's findings offer valuable guidance for clinicians in selecting effective second-line regimens, ensuring the best possible outcomes for their patients.

Finding the Oasis of Optimal Treatment: A Collaborative Approach to HIV Management

Individuals with HIV should work closely with their healthcare provider to develop a personalized treatment plan. This collaborative approach, much like a camel relying on a trusted guide to navigate the desert, ensures that the most appropriate treatment options are selected and that potential treatment failures are addressed promptly.

Dr.Camel's Conclusion

This study provides a valuable resource for clinicians treating patients with HIV who experience treatment failure with first-line therapies. It's like having a desert map that guides you to the most promising oases, ensuring you have the tools to navigate the complex landscape of HIV management. The study highlights the importance of carefully considering second-line ART regimens and the need to adapt treatment strategies as needed to optimize treatment outcomes.

Date :
  1. Date Completed 2010-07-27
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

20556768

DOI: Digital Object Identifier

10.1002/14651858.CD006517.pub3

SNS
PICO Info
in preparation
Languages

English

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