Radiotherapy alone or with concomitant daily low-dose carboplatin in locally advanced, unresectable head and neck cancer: definitive results of a phase III study with a follow-up period of up to ten years.

Author: AllisSimona, BeltramoGiancarlo, FossatiPiero, GabrieleAnna Maria, GabrielePietro, La PortaMaria Rosa, MelanoAntonella, MoroGregorio, OrecchiaRoberto, RagonaRiccardo, RampinoMonica, RicardiUmberto, Ruo ReddaMaria Grazia, TessaMariella

Paper Details 
Original Abstract of the Article :
Radiotherapy is the conventional treatment for locally advanced inoperable head and neck squamous cell carcinoma. However, the poor therapeutic results justify the development of radiochemotherapy combinations. In an attempt to improve local control and survival in patients with stage III and IV unr...See full text at original site
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引用元:
https://doi.org/10.1177/030089161009600210

データ提供:米国国立医学図書館(NLM)

Investigating the Effectiveness of Radiotherapy Combined with Carboplatin for Head and Neck Cancer

The treatment of locally advanced inoperable head and neck squamous cell carcinoma, a challenging cancer to treat, has long been a focus of research. This study delves into the potential benefits of combining radiotherapy with low-dose carboplatin, a chemotherapy drug, to improve local control and survival rates in patients with stage III and IV head and neck cancer. The study design involves a prospective, multicentric, randomized trial, providing a strong foundation for evaluating the efficacy of this treatment approach.

Promising Results for Head and Neck Cancer Treatment

The study highlights the potential of combining radiotherapy with low-dose carboplatin as a viable treatment option for advanced head and neck cancer. This approach offers hope for improving outcomes for patients grappling with this aggressive form of cancer. It's like finding a hidden spring in the desert, offering a refreshing and potentially life-sustaining solution.

Implications for Head and Neck Cancer Treatment

This study suggests that combining radiotherapy with low-dose carboplatin could offer a more effective approach for treating advanced head and neck cancer. This approach could lead to better local control and potentially improve survival rates for patients diagnosed with this challenging disease. This is a significant finding, like discovering a new trail that leads to a fertile oasis in the midst of a barren desert.

Dr.Camel's Conclusion

This research sheds light on the potential benefits of combining radiotherapy with low-dose carboplatin for treating advanced head and neck cancer. While further research is needed, this approach holds promise for improving outcomes and offering hope for patients battling this challenging disease. This is a fascinating discovery, like unearthing an ancient artifact that reveals a forgotten chapter in the history of cancer treatment.

Date :
  1. Date Completed 2010-07-08
  2. Date Revised 2022-10-07
Further Info :

Pubmed ID

20572581

DOI: Digital Object Identifier

10.1177/030089161009600210

Related Literature

SNS
PICO Info
in preparation
Languages

English

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