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Effectiveness and safety of high-dose valsartan monotherapy in hypertension treatment: the ValTop study.
Author: AsmarRoland, BiloGrzegorz, Di GiovanniRobert, KandraAlbert, MengdenThomas, ParatiGianfranco
Original Abstract of the Article :
Early combination therapy is increasingly recommended in hypertension management because of increased risk of adverse effects with high-dose monotherapy. However, this risk is not necessarily increased for high doses of angiotensin receptor blockers (ARB). ValTop study compared efficacy and safety o...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1038/hr.2010.120
データ提供:米国国立医学図書館(NLM)
High-Dose Valsartan Monotherapy for Hypertension
The battle against hypertension, a silent but powerful foe, is a constant struggle. This research explores the effectiveness and safety of high-dose valsartan monotherapy, a single-drug treatment, for managing hypertension. The study is like a well-equipped caravan venturing into the desert, seeking the most effective approach to combat this widespread condition.
A Viable Option for Hypertension Management
The researchers found that high-dose valsartan was both safe and effective in managing mild-to-moderate hypertension, even for patients who had not initially responded well to lower doses. The findings, like a refreshing oasis in the desert, offer a viable option for treating hypertension without the need for multiple medications.
Balancing Efficacy and Safety
This study underscores the importance of carefully balancing the effectiveness of a treatment with its potential side effects. The researchers demonstrated that high-dose valsartan provided significant blood pressure reduction without increasing the risk of adverse events. This finding, like a well-traveled desert route, provides a safe and effective path for managing hypertension.
Dr. Camel's Conclusion
This research offers a compelling case for high-dose valsartan monotherapy as a viable treatment option for hypertension. Like a skilled caravan leader, this study provides clinicians with a roadmap for effectively managing this condition while minimizing the risk of adverse effects.
Date :
- Date Completed 2011-02-01
- Date Revised 2015-11-19
Further Info :
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