Effectiveness and safety of high-dose valsartan monotherapy in hypertension treatment: the ValTop study.

Author: AsmarRoland, BiloGrzegorz, Di GiovanniRobert, KandraAlbert, MengdenThomas, ParatiGianfranco

Paper Details 
Original Abstract of the Article :
Early combination therapy is increasingly recommended in hypertension management because of increased risk of adverse effects with high-dose monotherapy. However, this risk is not necessarily increased for high doses of angiotensin receptor blockers (ARB). ValTop study compared efficacy and safety o...See full text at original site
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引用元:
https://doi.org/10.1038/hr.2010.120

データ提供:米国国立医学図書館(NLM)

High-Dose Valsartan Monotherapy for Hypertension

The battle against hypertension, a silent but powerful foe, is a constant struggle. This research explores the effectiveness and safety of high-dose valsartan monotherapy, a single-drug treatment, for managing hypertension. The study is like a well-equipped caravan venturing into the desert, seeking the most effective approach to combat this widespread condition.

A Viable Option for Hypertension Management

The researchers found that high-dose valsartan was both safe and effective in managing mild-to-moderate hypertension, even for patients who had not initially responded well to lower doses. The findings, like a refreshing oasis in the desert, offer a viable option for treating hypertension without the need for multiple medications.

Balancing Efficacy and Safety

This study underscores the importance of carefully balancing the effectiveness of a treatment with its potential side effects. The researchers demonstrated that high-dose valsartan provided significant blood pressure reduction without increasing the risk of adverse events. This finding, like a well-traveled desert route, provides a safe and effective path for managing hypertension.

Dr. Camel's Conclusion

This research offers a compelling case for high-dose valsartan monotherapy as a viable treatment option for hypertension. Like a skilled caravan leader, this study provides clinicians with a roadmap for effectively managing this condition while minimizing the risk of adverse effects.

Date :
  1. Date Completed 2011-02-01
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

20686486

DOI: Digital Object Identifier

10.1038/hr.2010.120

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Languages

English

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