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Treatment of chronic hepatitis B with interferon alfa-2b.

Author: BaumgartenR, FenglerJ D, Hintsche-KilgerB, KleinH, MarkusR, MeiselH, MüllerR, SchulzM, Von WussowP, WittenbergH

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study evaluated the effectiveness of interferon-alfa 2b in treating 58 patients with chronic hepatitis B. While 32% of the patients treated with interferon showed a partial response to therapy, with a significant decrease in viral markers and normalized liver enzymes, only 11% of untreated patients showed similar improvements. No patients experienced a reactivation of hepatitis after the virus was cleared. The study concludes that interferon-alfa 2b is a potential treatment for chronic hepatitis B, but further research is needed to optimize treatment and assess long-term outcomes.
Paper Details　
Original Abstract of the Article :
A total of 58 patients with histologically confirmed chronic viral hepatitis B and presence of hepatitis B surface antigen and hepatitis B virus DNA (HBV DNA) in the serum were randomized in a prospectively controlled trial. Thirty patients were treated with 3 megaunits of recombinant interferon alf...See full text at original site
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引用元：
https://doi.org/10.1016/0168-8278(90)90181-p

データ提供：米国国立医学図書館（NLM）

Interferon Alfa-2b for Chronic Hepatitis B: A Desert Oasis for Liver Health

This study investigates the effectiveness of interferon alfa-2b in treating chronic hepatitis B, a serious liver disease that can wreak havoc on the body like a relentless desert storm. The authors, like dedicated researchers, are seeking a solution to this debilitating condition, searching for a cure in the vast desert of medical knowledge.

A Beacon of Hope: Interferon Alfa-2b and Hepatitis B

The study found that interferon alfa-2b showed a significant positive effect in treating chronic hepatitis B, offering a glimmer of hope in the face of this challenging disease. It's like finding a life-giving oasis in the heart of a desolate desert. The authors have demonstrated that this treatment can effectively reduce viral activity and improve liver function.

A Healthy Liver: Prevention and Treatment

This research provides a valuable tool in the fight against chronic hepatitis B, highlighting the potential of interferon alfa-2b as a viable treatment option. It's like discovering a new source of water in the desert, offering a lifeline for those in need. It's a reminder that with continued research and innovation, we can overcome even the most formidable health challenges.

Dr.Camel's Conclusion

This study offers a glimmer of hope in the fight against chronic hepatitis B. It's like finding a precious oasis in the heart of a desert, providing a source of life and healing. The research highlights the potential of interferon alfa-2b as an effective treatment option, offering a new path to recovery for those affected by this serious disease.

Date :
  1. Date Completed 1991-04-30
  2. Date Revised 2019-08-17
Further Info :

Pubmed ID

2079572

DOI: Digital Object Identifier

10.1016/0168-8278(90)90181-p

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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