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Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and children.

Author: DucharmeFrancine M, FitzgeraldJ Mark, LemièreCatherine, QuonBradley S, ShahidiNeal

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

A review of 5 randomized controlled trials (RCTs) involving 1250 patients with mild to moderate asthma assessed the effectiveness of increasing inhaled corticosteroids (ICS) at the onset of asthma exacerbations. In adults, increasing ICS doses to 1000 to 2000 mcg/day did not significantly reduce the need for rescue oral corticosteroids. Further research is needed to assess the effectiveness of increased ICS doses in children.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Written action plans providing guidance in the early treatment of asthma exacerbations have traditionally advocated doubling of inhaled corticosteroids (ICS) as one of the first steps in treatment. OBJECTIVES: To compare the clinical effectiveness of increasing the dose of ICS versus ke...See full text at original site
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引用元：
https://doi.org/10.1002/14651858.CD007524.pub2

データ提供：米国国立医学図書館（NLM）

Inhaled Corticosteroids: Doubling the Dose for Asthma Exacerbations

Asthma, a chronic respiratory condition, can be quite the whirlwind, especially when exacerbations occur. Researchers are always looking for ways to manage these flare-ups, and this study delves into the effectiveness of increasing inhaled corticosteroids (ICS) as a strategy for controlling asthma exacerbations.

This research examined the effectiveness of increasing ICS doses versus maintaining the usual maintenance dose in adults and children experiencing asthma exacerbations. The study found that increasing ICS doses did not significantly reduce the need for rescue oral corticosteroids. This suggests that doubling the dose of inhaled corticosteroids might not be the most effective approach for managing asthma exacerbations.

More Research Needed on ICS Dose Strategies

The study's findings suggest that while increasing inhaled corticosteroids might not offer a dramatic reduction in the need for rescue medications, further research is warranted. Perhaps exploring other strategies for managing asthma exacerbations is necessary. It's like trying to navigate a sandstorm in the desert, where you need to find the right approach to avoid getting lost in the chaos.

Navigating the Sandstorm of Asthma Exacerbations

This research provides valuable insights for those living with asthma. While increasing inhaled corticosteroids at the onset of an exacerbation might not always be the solution, it's important to work closely with your healthcare provider to develop a personalized asthma action plan. This plan should include strategies for managing exacerbations, including the appropriate use of medication and other treatments.

Dr. Camel's Conclusion

It seems like we need to explore other strategies for managing asthma exacerbations, a journey that requires us to go beyond the familiar terrain and find new ways to tackle the challenges of this complex condition.

Date :
  1. Date Completed 2010-11-30
  2. Date Revised 2018-12-21
Further Info :

Pubmed ID

20927759

DOI: Digital Object Identifier

10.1002/14651858.CD007524.pub2

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・Effective treatment of asthma
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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