Inhalational therapy for pulmonary arterial hypertension: current status and future prospects.

Author: AhsanFakhrul, GuptaVivek

Paper Details 
Original Abstract of the Article :
This review summarizes the pathophysiology and current therapeutic and drug delivery strategies for pulmonary arterial hypertension (PAH), a rare but devastating disorder of the pulmonary circulation affecting 50,000 to 100,000 persons in the United States. Chief clinical features of PAH include inc...See full text at original site
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引用元:
https://doi.org/10.1615/critrevtherdrugcarriersyst.v27.i4.20

データ提供:米国国立医学図書館(NLM)

Inhalational Therapy: A Breath of Fresh Air for Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH), a rare but devastating disorder, is a formidable foe, like a sandstorm engulfing a desert traveler. It affects the pulmonary circulation, causing increased pressure in the arteries of the lungs, leading to shortness of breath, fatigue, and even heart failure. This review explores the current and future prospects of inhalational therapy for PAH, seeking a safe and effective treatment akin to finding a refreshing oasis in the midst of a relentless sandstorm.

A New Frontier in PAH Treatment

This review examines the pathophysiology and current therapeutic strategies for PAH, highlighting the limitations of conventional treatments. The researchers delve into the potential of inhalational drug delivery, a promising approach that allows for localized delivery of medications, minimizing systemic side effects. The review examines the recent approval of inhalable iloprost (Ventavis®) for PAH treatment and explores other potential inhalable medications like PGE1, treprostinil, vasoactive intestinal peptide, and fasudil. This review provides a roadmap for the development of inhalable PAH therapies, offering a beacon of hope for patients suffering from this debilitating condition.

Empowering Patients with New Treatment Options

This review highlights the exciting potential of inhalational therapy for PAH, offering a breath of fresh air for patients facing this challenging condition. It's like discovering a hidden spring in the desert, providing a source of relief and hope. Further research is needed to optimize inhalational delivery systems and ensure the long-term safety and efficacy of these treatments, but this review offers a compelling vision for a future where PAH patients can breathe easier.

Dr.Camel's Conclusion

Inhalational therapy holds great promise for the treatment of pulmonary arterial hypertension, offering a much-needed oasis in the desert of this challenging condition. This review provides a valuable overview of current and future prospects, illuminating the path toward safer and more effective treatments that can improve the lives of PAH patients.
Date :
  1. Date Completed 2011-01-20
  2. Date Revised 2019-11-11
Further Info :

Pubmed ID

20932241

DOI: Digital Object Identifier

10.1615/critrevtherdrugcarriersyst.v27.i4.20

SNS
PICO Info
in preparation
Languages

English

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