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Infliximab therapy increases body fat mass in early rheumatoid arthritis independently of changes in disease activity and levels of leptin and adiponectin: a randomised study over 21 months.
Author: BrismarKerstin, EngvallInga-Lill, HafströmIngiäld, TengstrandBirgitta
Original Abstract of the Article :
Rheumatoid arthritis (RA) is associated with changes in body composition and bone mineral density (BMD). The purpose of the present study was to evaluate whether anti-TNF treatment in early RA has an impact on body composition and BMD besides that which could be achieved by intensive disease-modifyi...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991034/
データ提供:米国国立医学図書館(NLM)
Infliximab: Impact on Body Composition in Early Rheumatoid Arthritis
The field of [rheumatology] is constantly seeking to understand the multifaceted effects of [anti-TNF treatment] on patients with [rheumatoid arthritis]. This study investigates the impact of [infliximab] on [body composition and bone mineral density (BMD)] in individuals with [early rheumatoid arthritis]. Researchers conducted a [randomized study over 21 months] comparing the effects of infliximab to [intensive disease-modifying anti-rheumatic drug (DMARD) combination therapy]. They found that [infliximab therapy increased body fat mass] independently of changes in disease activity and levels of leptin and adiponectin. The study highlighted [the potential for infliximab to influence body composition] in patients with early rheumatoid arthritis.
Infliximab: A New Perspective on Body Composition in Rheumatoid Arthritis
This research provides a new perspective on the effects of [infliximab] on body composition in patients with rheumatoid arthritis. The study's findings demonstrate [the potential for infliximab to increase body fat mass].
Navigating the Shifting Sands of Rheumatoid Arthritis Treatment
Treating rheumatoid arthritis can be like navigating a desert with ever-changing landscapes. This study helps us understand the [impact of infliximab on body composition] and navigate the complex terrain of rheumatoid arthritis treatment.
Dr. Camel's Conclusion
This study offers a glimpse into the multifaceted effects of infliximab on body composition in rheumatoid arthritis. The researchers have illuminated a new aspect of this complex disease, providing valuable insights for clinicians managing patient care.
Date :
- Date Completed 2011-03-31
- Date Revised 2022-03-30
Further Info :
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