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A phase I clinical trial of intraperitoneal thiotepa for refractory ovarian cancer.
Author: HowellS B, KirmaniS, LooD, McVeyL
Original Abstract of the Article :
Treatment options for patients with ovarian cancer who have failed systemic and intraperitoneal (ip) cisplatin-based chemotherapy are limited. We conducted a phase I clinical study of ip thiotepa in patients with refractory ovarian cancer to determine the maximum tolerated dose (MTD). Ten patients w...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/0090-8258(90)90136-9
データ提供:米国国立医学図書館(NLM)
Intraperitoneal Thiotepa for Refractory Ovarian Cancer: A New Frontier
Refractory ovarian cancer, a formidable foe, can feel like a desert mirage, elusive and difficult to conquer. This research explores the potential of intraperitoneal thiotepa as a treatment option for patients with ovarian cancer who have failed conventional therapies. The researchers conducted a phase I clinical trial to determine the maximum tolerated dose of intraperitoneal thiotepa and assess its safety and efficacy in this challenging patient population. This research offers hope for new treatment avenues for those facing this difficult diagnosis.
Intraperitoneal Thiotepa: A Promising Treatment Option for Refractory Ovarian Cancer
The phase I trial results suggest that intraperitoneal thiotepa is well tolerated and has shown clinical activity in heavily pretreated patients with refractory ovarian cancer. This promising finding offers hope for patients who have exhausted other treatment options, providing a potential oasis in the desert of their disease.
Navigating the Desert of Ovarian Cancer: Seeking Hope and Support
Ovarian cancer, like a desert trek, can be a challenging and arduous journey. Seeking a second opinion, exploring clinical trials, and engaging in support groups can provide invaluable resources and guidance for patients and their families, offering hope and strength in the face of adversity.
Dr. Camel's Conclusion
This research presents a potential glimmer of hope for patients with refractory ovarian cancer, offering a new path through the desert of this challenging disease. As we continue to explore new treatment options, it is important to remain optimistic and seek the support of healthcare professionals and loved ones in navigating this difficult journey.
Date :
- Date Completed 1990-05-07
- Date Revised 2019-08-24
Further Info :
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English
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