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Enhancing effect of pretreatment with topical niacin in the treatment of rosacea-associated erythema by 585-nm pulsed dye laser in Koreans: a randomized, prospective, split-face trial.

Author: ChoS B, KimT G, LeeJ H, LeeS J, OhS H, RohH J

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study found that pretreatment with topical niacin enhanced the effect of 585-nm pulsed dye laser (PDL) treatment for rosacea-associated erythema in Korean patients. While there was no significant difference in the improvement of objective erythema between the two sides, the niacin pretreatment side showed a significantly higher overall clinical improvement and patient satisfaction.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Rosacea is a chronic dermatosis that is usually confined to the face. A pulsed dye laser (PDL) system has been proven to be effective in treating rosacea-associated erythema and telangiectasias. Niacin is a cutaneous vasodilator that can increase the chromophore through increased blood f...See full text at original site
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引用元：
https://doi.org/10.1111/j.1365-2133.2010.10174.x

データ提供：米国国立医学図書館（NLM）

Niacin: A Desert Oasis for Rosacea-Related Erythema

Rosacea, a skin condition that often makes the face feel like it's walking across hot sands, is notoriously difficult to treat. Pulsed dye laser (PDL) therapy has shown promise, but for those with darker skin tones, the results can be less impactful. The researchers in this study sought a way to amplify the effectiveness of PDL treatment for Korean patients with rosacea, a condition that can feel like a constant desert wind whipping across their faces.

Boosting the Effectiveness of PDL Therapy

The researchers discovered that applying topical niacin, a natural vasodilator, before PDL treatment could significantly enhance its effectiveness. This finding is like adding a powerful, but gentle, desert wind to propel the laser's healing effects, bringing about a more noticeable improvement in rosacea-related erythema.

A Personalized Approach to Rosacea Treatment

This study highlights the importance of a personalized approach to treating rosacea, taking into account individual skin tones and sensitivities. While niacin has proven to be a useful adjunct to PDL therapy, further research is needed to understand its long-term benefits and potential side effects.

Dr.Camel's Conclusion

This study offers a valuable tool for treating rosacea, particularly for those with darker skin tones. It provides a reminder that the desert of skin conditions is vast and diverse, requiring a multifaceted approach to find the most effective treatment options for each individual.

Date :
  1. Date Completed 2011-05-17
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

21143465

DOI: Digital Object Identifier

10.1111/j.1365-2133.2010.10174.x

Related Literature

Article Analysis
・Effective treatment of rosacea
SNS
PICO Info
in preparation
Languages

English

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