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Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis.

Author: WilhelmusKirk R

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Trifluridine and acyclovir were more effective than idoxuridine or vidarabine in treating acute HSV epithelial keratitis. In a review of 106 comparative trials involving 5872 eyes, trifluridine and acyclovir were found to be superior in promoting corneal healing.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Eye disease due to herpes simplex virus (HSV) commonly presents as epithelial keratitis. OBJECTIVES: To compare the relative effectiveness of antiviral agents, interferon, and corneal débridement in the treatment of acute HSV epithelial keratitis. SEARCH STRATEGY: We searched CENTRAL (...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/21154352

データ提供：米国国立医学図書館（NLM）

Antiviral Treatment and Other Therapeutic Interventions for Herpes Simplex Virus Epithelial Keratitis

This systematic review comprehensively examines the efficacy of antiviral agents, interferon, and corneal débridement in treating acute herpes simplex virus (HSV) epithelial keratitis, a common eye disease. The study analyzed data from 106 comparative treatment trials involving 5872 eyes, evaluating the effectiveness of different interventions in promoting corneal healing over a two-week period. The review provides evidence-based recommendations for clinicians regarding the optimal treatment strategies for HSV epithelial keratitis.

Navigating the Landscape of HSV Keratitis Treatment: A Review of the Evidence

The systematic review offers a comprehensive and up-to-date overview of the current evidence regarding the treatment of HSV epithelial keratitis. It provides clinicians with a valuable resource to guide their treatment decisions, comparing the effectiveness of different antiviral agents, interferon, and corneal débridement. The review highlights the importance of selecting the most appropriate treatment strategy based on individual patient characteristics and the specific presentation of the disease.

Finding Clarity in the Treatment of HSV Keratitis: A Journey Through the Evidence

This research underscores the importance of evidence-based medicine in guiding clinical practice. The systematic review provides clinicians with a valuable tool to navigate the complex landscape of HSV epithelial keratitis treatment, ensuring that patients receive the most effective and appropriate care. As a wise old camel, I’ve learned that the journey to optimal outcomes often involves relying on the insights gained from rigorous research and evidence-based decision-making.

Dr.Camel's Conclusion

This comprehensive systematic review provides a valuable resource for clinicians managing HSV epithelial keratitis. It highlights the importance of selecting the most effective antiviral agent based on the specific presentation of the disease and individual patient characteristics. Remember, the search for effective treatments often involves navigating a vast expanse of information, and the results of systematic reviews can serve as valuable guideposts in our quest for optimal patient care.
Date :
  1. Date Completed 2011-02-10
  2. Date Revised 2023-11-04
Further Info :

Pubmed ID

21154352

DOI: Digital Object Identifier

NIHMS753011

SNS
PICO Info
in preparation
Languages

English

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