Low-cumulative dose isotretinoin treatment in mild-to-moderate acne: efficacy in achieving stable remission.

Author: BettoliV, BorghiA, GiariS, MantovaniL, MinghettiS, VirgiliA

Paper Details 
Original Abstract of the Article :
BACKGROUND: Aimed at the reduction of post-treatment relapse of severe acne, the cumulative dose of oral isotretinoin should be ≥120 mg/kg. However, data on the appropriate oral isotretinoin treatment regimen in mild and moderate acne are lacking. OBJECTIVE: The purpose of this study was to determi...See full text at original site
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引用元:
https://doi.org/10.1111/j.1468-3083.2010.03933.x

データ提供:米国国立医学図書館(NLM)

Isotretinoin: A Long-Term Oasis for Acne

This research ventures into the vast landscape of acne, a common skin condition that can have a significant impact on self-esteem and quality of life. The study investigates the effectiveness of isotretinoin, a potent oral medication, in achieving long-term remission of acne. The findings reveal that a lower cumulative dose of isotretinoin can be effective in inducing stable remission, offering a potential alternative to higher-dose regimens.

A Gentle Oasis: Minimizing Side Effects

The study found that a lower cumulative dose of isotretinoin, compared to traditional high-dose regimens, was effective in achieving long-term remission of acne. This is like finding a smaller, yet refreshing oasis in the desert, offering relief from the intense heat without the need for a massive water source. The findings suggest that a lower-dose approach may minimize the potential side effects associated with isotretinoin therapy.

Navigating the Desert of Acne: Personalized Treatment

The study highlights the importance of individualizing isotretinoin treatment regimens, considering the severity of acne and the patient's tolerance to the medication. This is like customizing a caravan for a specific desert journey, ensuring that it is well-equipped and suited to the unique challenges of the terrain. The findings emphasize the need for personalized care and careful monitoring to optimize treatment outcomes and minimize potential side effects.

Dr.Camel's Conclusion

This study suggests that a lower cumulative dose of isotretinoin may be an effective and potentially safer approach to achieving long-term remission of acne. The findings highlight the importance of individualizing treatment regimens and considering the potential benefits and risks of different dose schedules. This research provides valuable insights into the management of acne, offering a potential oasis of relief and a path toward a healthier and more confident skin.
Date :
  1. Date Completed 2011-12-05
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

21198947

DOI: Digital Object Identifier

10.1111/j.1468-3083.2010.03933.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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