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The effects of golimumab on radiographic progression in rheumatoid arthritis: results of randomized controlled studies of golimumab before methotrexate therapy and golimumab after methotrexate therapy.

Author: BaratelleAnna, BeutlerAnna, ConaghanPhilip G, EmeryPaul, FleischmannRoy, GenoveseMark C, HsiaElizabeth C, KeystoneEdward C, RahmanMahboob U, XuWeichun, van der HeijdeDésirée

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Golimumab in combination with methotrexate (MTX) significantly inhibited radiographic progression in methotrexate-naive patients with rheumatoid arthritis (RA) compared to MTX alone.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To evaluate the effects of golimumab on radiographic progression in patients with rheumatoid arthritis (RA). METHODS: Methotrexate (MTX)-naive patients (in the Golimumab Before Employing Methotrexate as theFirst-Line Option in the Treatment of Rheumatoid Arthritis of Early Onset [GO-BEFO...See full text at original site
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引用元：
https://doi.org/10.1002/art.30263

データ提供：米国国立医学図書館（NLM）

Slowing the Progression of Rheumatoid Arthritis: A Desert of Hope

This study focuses on the treatment of rheumatoid arthritis, a chronic inflammatory disease that can cause joint damage and disability. It’s like a camel caravan struggling through a desert of pain and inflammation, seeking to find a way to slow the progression of this debilitating condition. The researchers investigated the effects of the medication golimumab on the progression of rheumatoid arthritis, examining its impact on radiographic joint damage.

A Possible Oasis in the Desert of Arthritis

The study discovered that golimumab, in combination with methotrexate, was more effective in slowing the progression of rheumatoid arthritis than methotrexate alone. It’s like finding a hidden oasis in the desert of arthritis, offering a potential reprieve from the relentless march of joint damage.

Navigating the Challenges of Rheumatoid Arthritis

This study underscores the importance of early diagnosis and treatment for rheumatoid arthritis, emphasizing the potential benefits of medications like golimumab in slowing the progression of the disease. It’s like having a guide to help you navigate the complexities of this chronic condition.

Dr.Camel's Conclusion

This study offers a beacon of hope for individuals with rheumatoid arthritis, demonstrating the potential of golimumab to slow the progression of the disease and preserve joint function. The findings highlight the importance of early diagnosis and treatment, and the potential of medications to improve the quality of life for patients with this challenging condition.

Date :
  1. Date Completed 2011-08-05
  2. Date Revised 2022-03-09
Further Info :

Pubmed ID

21305524

DOI: Digital Object Identifier

10.1002/art.30263

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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