Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children.

Author: BusseWilliam W, CalatroniAgustin, ChmielJames F, GergenPeter J, GernJames E, GruchallaRebecca S, KattanMeyer, LiuAndrew H, MitchellHerman E, MorganWayne J, PongracicJacqueline A, SorknessChristine A, SteinbachSuzanne F, SzeflerStanley J, TeachStephen J, ThompsonKatherine M, TogiasAlkis

Paper Details 
Original Abstract of the Article :
BACKGROUND: Research has underscored the effects of exposure and sensitization to allergens on the severity of asthma in inner-city children. It has also revealed the limitations of environmental remediation and guidelines-based therapy in achieving greater disease control. METHODS: We enrolled inn...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/21410369

データ提供:米国国立医学図書館(NLM)

Omalizumab: A New Hope for Inner-City Children with Asthma

Asthma, a chronic respiratory condition, can significantly impact the lives of children, particularly those living in inner cities. This study explores the effectiveness of omalizumab, an anti-IgE antibody, in improving asthma control in inner-city children with persistent asthma. The authors conducted a randomized, double-blind, placebo-controlled trial, comparing the effects of omalizumab with placebo when added to standard asthma management guidelines. Their findings offer promising insights into the potential of omalizumab for managing asthma in this vulnerable population.

Omalizumab: A Potential Game-Changer for Asthma Management

The study found that omalizumab, when added to standard asthma management, significantly reduced asthma symptoms, including the number of days with asthma symptoms and the frequency of exacerbations. These improvements were observed despite reductions in the use of inhaled corticosteroids and long-acting beta-agonists, suggesting that omalizumab can provide additional benefits beyond those achieved with standard therapies. The study highlights the potential of omalizumab as a promising therapeutic option for improving asthma control in inner-city children.

Improving Asthma Care for Inner-City Children

This study provides valuable information for clinicians managing asthma in inner-city children. The authors' findings demonstrate the effectiveness of omalizumab in improving asthma control and reducing the need for other medications, offering a potential solution for managing this challenging condition. The study encourages further research into the long-term benefits of omalizumab and its potential to improve quality of life for inner-city children living with asthma.

Dr.Camel's Conclusion

This study, like a refreshing oasis in the arid landscape of asthma research, offers hope for inner-city children struggling with this chronic condition. Omalizumab, a new therapeutic tool, shows promise in improving asthma control and reducing the reliance on other medications. This research paves the way for a brighter future for these children, allowing them to breathe easier and live fuller lives.

Date :
  1. Date Completed 2011-03-24
  2. Date Revised 2022-03-21
Further Info :

Pubmed ID

21410369

DOI: Digital Object Identifier

NIHMS287236

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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