Botulinum toxin type B for sialorrhoea in children with cerebral palsy: a randomized trial comparing three doses.

Author: BascianiMario, CopettiMassimiliano, Di RienzoFilomena, FontanaAndrea, IntisoDomenico, PellegriniFabio

Paper Details 
Original Abstract of the Article :
AIM: The aim of the present study was to evaluate the efficacy and safety of three doses of botulinum toxin type B (BoNT-B) in reducing persistent sialorrhoea in children with cerebral palsy (CP). METHOD: Children with CP and refractory sialorrhoea were randomized to one of four groups: a control g...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1111/j.1469-8749.2011.03952.x

データ提供:米国国立医学図書館(NLM)

Botulinum Toxin Type B: A Potential Oasis for Sialorrhea in Children with Cerebral Palsy

Navigating the [challenges of cerebral palsy] can be a difficult journey for both patients and their families. This study, like a compassionate caregiver, investigated the effectiveness of [botulinum toxin type B (BoNT-B)] for reducing [sialorrhea (excessive drooling)] in children with [cerebral palsy]. Their [randomized trial] compared three different doses of BoNT-B, and found that, much like a well-placed watering hole in the desert, a [medium dose (3000 MU)] significantly improved drooling severity and frequency. This finding offers a beacon of hope for families seeking relief from this common symptom.

A Dose of Hope: Finding the Right Balance with BoNT-B

The study showed that a [medium dose of BoNT-B] was most effective in reducing [sialorrhea] in children with [cerebral palsy]. While a lower dose proved ineffective, the highest dose provided no additional benefit and resulted in more side effects. This finding, like a precise measurement of water in the desert, highlights the importance of finding the right balance for each patient.

Seeking Comfort in the Desert: Managing Sialorrhea with BoNT-B

This research suggests that [BoNT-B] may offer a valuable tool for managing [sialorrhea] in children with [cerebral palsy]. However, it's crucial to remember that each child is unique and requires individualized treatment. Like choosing the right path in the desert, careful consideration should be given to the potential benefits and risks associated with this treatment.

Dr.Camel's Conclusion

This study provides valuable insights into the potential benefits of BoNT-B for managing sialorrhea in children with cerebral palsy. Just as a camel learns to navigate the desert with resilience, this research helps families find a path towards better comfort and quality of life.

Date :
  1. Date Completed 2011-07-15
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

21413974

DOI: Digital Object Identifier

10.1111/j.1469-8749.2011.03952.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.