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HIV: primary and secondary prophylaxis for opportunistic infections.

Author: AbergJudith, PowderlyWilliam

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Prophylaxis against opportunistic infections is effective in people with HIV infection and a CD4 count less than 250/mm(3). This review presents information on the effectiveness and safety of various interventions, including aciclovir, antituberculosis prophylaxis, atovaquone, azithromycin, clarithromycin, fluconazole, and trimethoprim-sulfamethoxazole.
Paper Details　
Original Abstract of the Article :
INTRODUCTION: Opportunistic infections can occur in up to 40% of people with HIV infection and a CD4 count less than 250/mm(3), although the risks are much lower with use of highly active antiretroviral treatment. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the follow...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217757/

データ提供：米国国立医学図書館（NLM）

Prophylaxis for Opportunistic Infections in HIV: A Vital Strategy

HIV infection weakens the immune system, making individuals susceptible to a variety of opportunistic infections. Prophylaxis, the use of medication to prevent infection, plays a crucial role in managing HIV infection. This study provides a comprehensive review of the effectiveness and safety of different prophylactic strategies for various opportunistic infections in people living with HIV.

The review examined the evidence for prophylaxis against Pneumocystis jirovecii pneumonia (PCP), toxoplasmosis, tuberculosis, disseminated Mycobacterium avium complex (MAC) disease, cytomegalovirus (CMV), herpes simplex virus (HSV), varicella zoster virus (VZV), and invasive fungal disease. It also explored the effects of discontinuing prophylaxis in individuals on highly active antiretroviral treatment (HAART).

Protecting against Opportunistic Infections

The review highlights the importance of prophylactic strategies in preventing opportunistic infections in people living with HIV. Appropriate prophylaxis can significantly reduce the risk of serious complications and improve overall health outcomes.

Navigating HIV Treatment

If you're living with HIV, it's crucial to work closely with your healthcare provider to develop a comprehensive treatment plan that includes appropriate prophylaxis for opportunistic infections. This review provides valuable information about the effectiveness and safety of different prophylactic strategies, but the best approach will depend on your individual needs and medical history.

Dr.Camel's Conclusion

Just like a camel navigating a harsh desert environment, individuals living with HIV must be vigilant in protecting themselves from opportunistic infections. This study, like a well-stocked oasis offering vital supplies, provides valuable insights into the effectiveness of prophylactic strategies, reminding us that prevention is paramount in managing HIV infection.

Date :
  1. Date Completed 2016-04-22
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

21418688

DOI: Digital Object Identifier

PMC3217757

SNS
PICO Info
in preparation
Languages

English

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