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Cefazolin and enterobacteriaceae: rationale for revised susceptibility testing breakpoints.

Author: , TurnidgeJohn D

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Cefazolin is an antibiotic that is used to treat bacterial infections. New guidelines for the use of cefazolin against Enterobacteriaceae have been developed based on recent research. These guidelines recommend increasing the minimum inhibitory concentration for cefazolin. This change is linked to a recommended adult dosage of 2 g every 8 hours intravenously.
Paper Details　
Original Abstract of the Article :
Clinical and Laboratory Standards Institute breakpoints for cefazolin against Enterobacteriaceae that were published in January 2010 have been revised by the Subcommittee on Antimicrobial Susceptibility Testing, based on the examination of recent data about in vitro activity, pharmacokinetic-pharmac...See full text at original site
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引用元：
https://doi.org/10.1093/cid/cir031

データ提供：米国国立医学図書館（NLM）

Cefazolin and Enterobacteriaceae: Navigating a Changing Desert

The world of antibiotic resistance is a constantly shifting desert landscape. This study examines the need for revised susceptibility testing breakpoints for cefazolin against Enterobacteriaceae, a group of bacteria that can cause a range of infections. The authors highlight the importance of staying ahead of evolving resistance patterns and adjusting interpretive criteria to ensure accurate diagnosis and effective treatment. They advocate for a more robust approach to testing, ensuring appropriate antibiotic choices and maximizing patient outcomes in the face of a constantly evolving microbial landscape.

Staying Ahead of the Curve: Revised Susceptibility Testing Breakpoints

This study emphasizes the importance of staying ahead of the curve in the fight against antibiotic resistance. By revising susceptibility testing breakpoints for cefazolin against Enterobacteriaceae, clinicians can ensure more accurate diagnoses and appropriate antibiotic choices, leading to more effective treatment and improved patient outcomes.

Navigating the Desert of Antibiotic Resistance

Antibiotic resistance is a complex and challenging desert, requiring constant vigilance and adaptation. This study highlights the importance of evolving testing methods and interpretive criteria to ensure effective antibiotic use and combat the growing threat of resistance. By understanding the shifting sands of antibiotic resistance, we can better navigate this critical medical landscape.

Dr.Camel's Conclusion

The desert of antibiotic resistance is a constantly shifting landscape, demanding a vigilant and adaptable approach. This study emphasizes the importance of revising susceptibility testing breakpoints to ensure accurate diagnosis and effective treatment. It reminds us that in the fight against antibiotic resistance, we must constantly adapt and evolve our strategies to protect our health and combat this ever-present threat.
Date :
  1. Date Completed 2011-07-18
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

21427400

DOI: Digital Object Identifier

10.1093/cid/cir031

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Languages

English

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