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Prophylactic intragraft injection of nicardipine prior to saphenous vein graft percutaneous intervention for the prevention of no-reflow: a review and comparison to protection devices.

Author: HabibzadehMohammad Reza, MovahedMohammad Reza, ThaiHoang

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review discusses the use of intracoronary nicardipine for prevention of no-reflow during saphenous vein graft intervention. Nicardipine is considered the best option in preventing no-reflow due to its minimal systemic side effects, modest negative inotropic and chronotropic effects, duration of action and feasibility of use.
Paper Details　
Original Abstract of the Article :
No-reflow is a failure to restore normal coronary flow despite appropriate treatment of coronary obstruction. It is most commonly seen during interventions in saphenous vein grafts and is associated with poor outcome. The cause of no-reflow is complex and multifactorial. Various mechanisms including...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/21562350

データ提供：米国国立医学図書館（NLM）

Nicardipine for No-Reflow: Preventing a Deadly Desert Mirage

No-reflow is a serious complication that can occur during coronary interventions, particularly in saphenous vein grafts. It's like a deadly desert mirage, where blood flow is blocked, threatening the survival of the heart. This study explores the potential of intragraft nicardipine injection for preventing no-reflow.

The authors discuss the complex mechanisms underlying no-reflow, including vasospasm and distal embolization. They argue that intracoronary nicardipine, a calcium channel blocker, offers a promising approach to preventing this complication. This is like using a compass and map to navigate the treacherous terrain of the heart, ensuring a safe and successful journey.

A Promising Strategy for Preventing No-Reflow

The study highlights the potential benefits of intragraft nicardipine injection in reducing the risk of no-reflow during saphenous vein graft interventions. This approach could improve patient outcomes and reduce the risk of heart damage.

Dr. Camel's Conclusion

This study is like a camel caravan venturing into a desert with hidden dangers, seeking to navigate the treacherous terrain of no-reflow. The research reveals the potential of intragraft nicardipine injection as a valuable tool for preventing this life-threatening complication, offering a beacon of hope in the quest for safer and more effective coronary interventions.

Date :
  1. Date Completed 2011-09-30
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

21562350

DOI: Digital Object Identifier

21562350

Related Literature

Article Analysis
・Side Effects of nicardipine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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