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Effects of antipsychotic treatment on psychopathology and motor symptoms. A placebo-controlled study in healthy volunteers.

Author: GründerGerhard, GurRuben, HiemkeChristoph, SchifflKatharina, SchornHolger, VernalekenIngo, VeselinovićTanja, ZernigGerald

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

There's growing interest in understanding the various symptoms of schizophrenia and how they respond to medication. Negative symptoms and cognitive problems in particular are often resistant to current antipsychotic treatments. Interestingly, some negative symptoms of psychosis resemble the side effects of antipsychotic medications that block dopamine.
Paper Details　
Original Abstract of the Article :
There is increased interest in elucidating the range of symptoms of schizophrenia and their response to treatment with medications. Particularly negative and cognitive symptoms are often resistant to the therapy with currently available antipsychotics. There are even similarities between negative sy...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
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引用元：
https://doi.org/10.1007/s00213-011-2368-3

データ提供：米国国立医学図書館（NLM）

Antipsychotic Treatment: Navigating the Shifting Sands of Schizophrenia

The study delves into the intricate world of schizophrenia, a complex mental illness that's like a vast desert of symptoms, some hidden and elusive. It focuses on the effectiveness of antipsychotic medications in treating these symptoms, particularly negative and cognitive ones, which can be like mirages in the desert, difficult to grasp and treat. The researchers conducted a placebo-controlled study in healthy volunteers to better understand how antipsychotic drugs impact the diverse symptoms of schizophrenia. They observed similarities between negative symptoms in psychosis and the side effects of antidopaminergic antipsychotic drugs, a finding that's like discovering two distinct but interconnected oasis in the desert.

Antipsychotic Treatment: A Search for Balance in the Desert

The study emphasizes the need for further research into effective treatments for negative and cognitive symptoms in schizophrenia. It's like searching for a path through the shifting sands to find the best approach for managing these complex aspects of the disease.

Antipsychotic Treatment: A Guide for Navigating the Desert

The study underscores the importance of carefully evaluating the risks and benefits of different antipsychotic medications. It's like choosing the right camel for a journey through the desert. Each drug has its own set of potential side effects, and finding the right balance is crucial for achieving optimal outcomes.

Dr.Camel's Conclusion

This study helps us better understand the intricate landscape of schizophrenia and the challenges of treating its diverse symptoms. It's a reminder that the search for effective treatments is an ongoing journey, much like a camel trek across the desert, with twists and turns along the way. The ultimate goal is to find solutions that offer a pathway to better health and well-being for those affected by this complex disease.

Date :
  1. Date Completed 2012-03-26
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

21643673

DOI: Digital Object Identifier

10.1007/s00213-011-2368-3

Related Literature

Article Analysis
・Effective treatment of schizophrenia
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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