Efficacy and safety of perioperative pregabalin for post-operative pain: a meta-analysis of randomized-controlled trials.

Author: CateloyF, EngelmanE

Paper Details 
Original Abstract of the Article :
We calculated in a meta-analysis the effect size for the reduction of post-operative pain and post-operative analgesic drugs, which can be obtained by the perioperative administration of pregabalin. Three end-points of efficacy were analysed: early (6 h-7 days) post-operative pain at rest (17 studie...See full text at original site
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引用元:
https://doi.org/10.1111/j.1399-6576.2011.02471.x

データ提供:米国国立医学図書館(NLM)

Pregabalin: A Double-Edged Sword in Post-Operative Pain Management

This research delves into the world of [post-operative pain management] and explores the use of [pregabalin] in reducing [pain and analgesic drug consumption]. The study, like a camel caravan navigating a vast desert, examines the [efficacy and safety] of [pregabalin] in various [surgical settings]. The researchers conducted a [meta-analysis] of [randomized controlled trials], revealing that [pregabalin] can reduce [post-operative pain] and [analgesic drug consumption], but also comes with a [risk of adverse effects] such as [dizziness, light-headedness, and visual disturbances]. This comprehensive analysis provides valuable insights into the [potential benefits and drawbacks] of pregabalin in post-operative pain management.

A Balancing Act: Pain Relief with Caution

This research underscores the importance of [balancing the benefits and risks] of [pregabalin] in [post-operative pain management]. It's like navigating a desert; while [pregabalin] may offer an oasis of pain relief, we must also be aware of potential hazards. The study suggests that [pregabalin] can be effective in reducing [pain and analgesic drug consumption], but [close monitoring] is crucial to mitigate the risk of [adverse effects].

Navigating the Desert of Post-Operative Pain

This research emphasizes the need for [individualized treatment approaches] in managing [post-operative pain]. It's like navigating a vast desert; each traveler requires a unique approach to reach their destination. The study's findings suggest that [pregabalin] may be a valuable tool in the arsenal of [pain management], but it must be used with caution and careful consideration of the potential risks and benefits.

Dr.Camel's Conclusion

This research, like a wise camel, reminds us that even the most promising solutions can come with hidden challenges. The study sheds light on the complex interplay between pregabalin, post-operative pain, and potential adverse effects. By understanding the nuances of this medication and its potential impact, we can navigate the desert of pain management with greater wisdom and care.

Date :
  1. Date Completed 2012-03-25
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

21707548

DOI: Digital Object Identifier

10.1111/j.1399-6576.2011.02471.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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