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Raloxifene and tibolone in elderly women: a randomized, double-blind, double-dummy, placebo-controlled trial.

Author: JacobsenDidy E, MelisRené J F, Olde RikkertMarcel G M, VerhaarHarald J J

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This randomized controlled trial evaluated the effects of raloxifene and tibolone on body mass density, handgrip strength, and other frailty components in older women. Both treatments significantly increased body mass density but had no effect on handgrip strength. Raloxifene also had positive effects on verbal memory and health status.
Paper Details　
Original Abstract of the Article :
OBJECTIVES: The authors' first aim was to study the effects of raloxifene and tibolone on body mass density, handgrip strength, and other secondary frailty components. The secondary aim was to compare the effects of raloxifene and tibolone and their safety in older women. DESIGN/SETTING/PARTICIPANT...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.1016/j.jamda.2011.05.005

データ提供：米国国立医学図書館（NLM）

Raloxifene and Tibolone: Navigating the Desert of Aging

As we navigate the desert of aging, seeking ways to maintain our strength and well-being, research into hormone therapy plays a crucial role. This study, like a caravan seeking a safe passage through the aging process, compares the effects of raloxifene and tibolone on bone density, muscle strength, and other aspects of frailty in elderly women. It's a quest to find the oasis of healthy aging.

Unveiling the Potential Benefits of Hormone Therapy

The study, like a careful explorer mapping a new terrain, reveals that both raloxifene and tibolone can significantly increase bone density in older women. This finding, like discovering a hidden oasis of strength, offers potential benefits for preventing osteoporosis and fractures. The study also suggests that raloxifene may have positive effects on verbal memory and overall health status, highlighting its potential benefits beyond bone health.

Embracing Healthy Aging

This research, like a compass guiding a traveler through the desert of aging, provides valuable insights into the potential benefits of hormone therapy for older women. It's a reminder that even in the midst of aging, there are opportunities to enhance our health and well-being. The study emphasizes the importance of personalized care and the need to consider the individual needs and preferences of each patient.

Dr.Camel's Conclusion

This study underscores the potential benefits of hormone therapy, particularly raloxifene, for older women. It's a reminder that the desert of aging can be navigated with a combination of knowledge, care, and appropriate interventions.

Date :
  1. Date Completed 2012-06-01
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

21741883

DOI: Digital Object Identifier

10.1016/j.jamda.2011.05.005

Related Literature

Article Analysis
・Effects of raloxifene
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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