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Treat ankylosing spondylitis with methazolamide.

Author: ChangXiaotian, YanXinfeng, ZhangYunzhong

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Methazolamide is an anti-carbonic anhydrase drug that can help to restrain bone resorption, a characteristic of ankylosing spondylitis (AS). This study evaluated the effectiveness and safety of methazolamide in treating patients with AS.
Paper Details　
Original Abstract of the Article :
Increased bone resorption and new bone information are two characteristics of ankylosing spondylitis (AS). Much evidence has shown that carbonic anhydrase inhibitors can restrain bone resorption. We had detected increased expression of carbonic anhydrase I (CA1) in synovium of patients with AS. This...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133847/

データ提供：米国国立医学図書館（NLM）

Methazolamide for Ankylosing Spondylitis

[Ankylosing spondylitis (AS)] is a chronic inflammatory disease that primarily affects the [spine]. This study investigates the potential of [methazolamide], a [carbonic anhydrase inhibitor], for the [treatment of AS]. The research explores the [efficacy and safety] of this medication based on the [increased expression of carbonic anhydrase I (CA1)] in [AS patients].

Methazolamide: A Potential Treatment for AS?

The study suggests that [methazolamide] may offer a [novel therapeutic approach] for [AS]. The medication's mechanism of action, targeting [CA1], aligns with the disease's pathophysiology involving [increased bone resorption].

AS Treatment: A Multifaceted Approach

While the findings suggest a potential role for [methazolamide] in [treating AS], it's crucial to remember that [AS treatment] often requires a [multifaceted approach]. This research highlights the importance of [individualized care] and considering the [benefits and risks] of different medications in consultation with healthcare professionals. It's like navigating a desert with a caravan – a successful journey requires planning, preparation, and adapting to unforeseen circumstances.

Dr. Camel's Conclusion

This research on methazolamide for AS is like a camel caravan discovering a hidden oasis offering a potential new source of relief. The findings suggest a promising avenue for treatment, but further research and careful consideration are crucial to ensure its effectiveness and safety for each patient.
Date :
  1. Date Completed 2011-10-27
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

21750646

DOI: Digital Object Identifier

PMC3133847

Related Literature

Article Analysis
・Side Effects of methazolamide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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