Improving mood with psychoanalytic and cognitive therapies (IMPACT): a pragmatic effectiveness superiority trial to investigate whether specialised psychological treatment reduces the risk for relapse in adolescents with moderate to severe unipolar depression: study protocol for a randomised controlled trial.

Author: ByfordSarah, DubickaBernadka, FonagyPeter, GoodyerIan M, HillJonathan, KelvinRaphael, ReynoldsShirley, RobertsChristopher, SeniorRobert, SucklingJohn, TargetMary, TsanchevaSonya, WilkinsonPaul

Overview

About 70% of teenagers with moderate to severe depression improve with a combination of therapy and fluoxetine (20-50mg), seeing symptom relief and improved social skills within 24 weeks. However, about 20% don't respond to treatment and 30% of those who do respond experience a relapse within two years. The best types of therapy, the factors that influence relapse risk, and the cost-effectiveness and safety of therapy are still unclear.

Paper Details　

Original Abstract of the Article :

Up to 70% of adolescents with moderate to severe unipolar major depression respond to psychological treatment plus Fluoxetine (20-50 mg) with symptom reduction and improved social function reported by 24 weeks after beginning treatment. Around 20% of non responders appear treatment resistant and 30%...See full text at original site

Dr.Camel's Paper Summary Blog

Investigating the Effectiveness of Psychological Therapies in Teen Depression

This research dives into the challenging world of teenage depression, a field where we're constantly seeking better solutions. The study uses a pragmatic approach, comparing different psychological therapies to see which ones are most effective in preventing relapse in adolescents with moderate to severe unipolar depression. Their goal is to find out if specialized psychological treatment can help these teens avoid going back to a depressed state after they initially respond to therapy and medication. The authors are particularly interested in exploring why some teens respond well to therapy, while others don't, and what factors can influence whether they relapse. This is like a treasure hunt in the desert of depression, where we're searching for the keys to help these teens thrive. The study also explores the cost-effectiveness and safety of these therapies, ensuring we find a solution that is both effective and practical.

A Better Understanding of Teen Depression

The findings suggest that specialized psychological treatment can be a valuable tool in helping adolescents with moderate to severe unipolar depression avoid relapses. This is good news because it offers hope that teens can manage their depression long-term. The study also emphasizes the importance of understanding individual factors that might influence relapse, like the specific type of therapy used and the teen's personal experiences. It's like learning how to navigate the vast desert of depression – every teen has their own unique path, and we need to tailor our approach to meet their individual needs.

Practical Implications for Teen Mental Health

This research highlights the importance of ongoing mental health support for teens who struggle with depression. It encourages us to look beyond just treating the immediate symptoms and consider the long-term well-being of these individuals. This means being attentive to their unique needs, recognizing that different approaches may work better for some than others, and providing ongoing support to help them stay well. It's like offering a camel a steady supply of water in the desert, ensuring they have the resources they need to stay hydrated and healthy.

Dr. Camel's Conclusion

This study is a beacon of hope in the vast desert of adolescent mental health. By focusing on the individual needs of teens, we can find the best paths to help them overcome depression and navigate towards a brighter future.