Formulation and evaluation of meloxicam niosomes as vesicular carriers for enhanced skin delivery.

Author: El-MenshaweShahira F, HusseinAmal K

Paper Details 
Original Abstract of the Article :
CONTEXT: Skin delivery of Meloxicam (MX) offers several advantages over the oral route which is associated with potential side effects. OBJECTIVES: The aim of this study was to develop transdermal MX in niosomes. MATERIALS AND METHODS: Vesicles prepared by thin film hydration method were character...See full text at original site
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引用元:
https://doi.org/10.3109/10837450.2011.598166

データ提供:米国国立医学図書館(NLM)

Meloxicam Niosomes: A Desert Oasis for Skin Delivery

Meloxicam (MX), a nonsteroidal anti-inflammatory drug (NSAID), is often used to treat pain and inflammation. Traditional oral administration of MX can lead to side effects, like a camel encountering a sandstorm during its journey. This study, like a camel seeking a new route through the desert, explored the potential of niosomes as vesicular carriers for enhanced skin delivery of MX. Researchers formulated MX-loaded niosomes and evaluated their ability to penetrate the skin and reduce inflammation. They found that MX niosomes significantly enhanced skin permeation and demonstrated superior anti-inflammatory activity compared to free MX.

Niosomes: A New Route for Drug Delivery

This study, like a caravan discovering a new trade route, highlights the potential of niosomes as effective carriers for delivering drugs to the skin. By encapsulating MX within niosomes, researchers were able to enhance its skin permeation and improve its therapeutic efficacy. This research opens doors for developing more effective and targeted drug delivery systems for topical applications.

Navigating the Desert of Skin Delivery: A Camel's Perspective

As a camel who has traversed many deserts, I understand the importance of finding the right path. This study emphasizes the need for innovative drug delivery systems to enhance the effectiveness and safety of topical medications. Niosomes, like a well-worn path through the desert, offer a promising route for delivering drugs directly to the skin, potentially leading to improved treatment outcomes.

Dr. Camel's Conclusion

This study demonstrates the potential of niosomes as a promising vehicle for transdermal delivery of MX, offering a new and potentially more effective approach to treating skin-related conditions. Continued research in this area may lead to the development of innovative drug delivery systems that improve patient outcomes and enhance quality of life.

Date :
  1. Date Completed 2013-12-23
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

21913880

DOI: Digital Object Identifier

10.3109/10837450.2011.598166

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SNS
PICO Info
in preparation
Languages

English

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