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Testing nicotine gum for ulcerative colitis patients. Experience with single-patient trials.

Author: HanauerS B, LashnerB A, SilversteinM D

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Nicotine gum may be an effective therapy for individual patients with ulcerative colitis who demonstrate an objective response with few adverse effects. In a double-blind randomized crossover trial, 3 of 7 patients, all former smokers, demonstrated sufficient improvement with nicotine gum compared to placebo.
Paper Details　
Original Abstract of the Article :
Epidemiologic studies have documented an association between nonsmoking and ulcerative colitis and case reports have demonstrated that symptoms improve with smoking and worsen with removal of a nicotine source. A double-blind randomized crossover trial for individual ulcerative colitis patients (sin...See full text at original site
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引用元：
https://doi.org/10.1007/BF01536795

データ提供：米国国立医学図書館（NLM）

Nicotine Gum for Ulcerative Colitis: A Patch of Green in the Desert of Inflammatory Bowel Disease

Ulcerative colitis, a chronic inflammatory bowel disease, is like a relentless desert wind that can cause persistent discomfort and inflammation. This study explores the potential of nicotine gum, a therapy often associated with smoking cessation, as a treatment for ulcerative colitis.

The researchers conducted a series of single-patient trials, evaluating the safety, efficacy, and patient acceptance of nicotine gum for individuals with ulcerative colitis. The study found that, in some patients, nicotine gum was associated with improvement in ulcerative colitis symptoms. The authors' findings suggest that nicotine gum might be a promising treatment option for certain patients with ulcerative colitis, although further research is needed to confirm its efficacy and determine the optimal dose.

A New Oasis: Exploring the Potential of Nicotine Gum

The study's findings offer a potential new avenue for treating ulcerative colitis. The researchers' work suggests that, while more research is needed, nicotine gum might offer a promising treatment option for certain patients with ulcerative colitis. The study's results encourage further investigation into the potential benefits and risks of nicotine gum for this challenging condition.

Navigating the Desert of Inflammatory Bowel Disease: Seeking Relief and Support

This research underscores the importance of exploring a range of treatment options for individuals with ulcerative colitis. The authors' findings highlight the need for continued research and exploration of new therapeutic approaches to address the unique needs of patients with this debilitating condition.

Dr. Camel's Conclusion

This study is a reminder that the search for effective treatments for inflammatory bowel disease is an ongoing one. The authors' findings suggest that nicotine gum might offer a promising treatment option for certain patients with ulcerative colitis, but further research is needed to confirm its efficacy and determine the optimal dose. The study's findings encourage us to continue exploring the vast desert of knowledge and innovation in the search for new and effective treatments for inflammatory bowel disease.

Date :
  1. Date Completed 1990-08-13
  2. Date Revised 2019-07-21
Further Info :

Pubmed ID

2194767

DOI: Digital Object Identifier

10.1007/BF01536795

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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