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Generation of reactive oxygen species during apoptosis induced by DNA-damaging agents and/or histone deacetylase inhibitors.

Author: BrodskáBarbora, HoloubekAleš

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Reactive oxygen species (ROS) play an important role in apoptosis induced by DNA-damaging agents in leukemia cell line CML-T1.
Paper Details　
Original Abstract of the Article :
Reactive oxygen species play an important role in the process of apoptosis in many cell types. In this paper, we analyzed the role of ROS in DNA-damaging agents (actinomycin D or decitabine), which induced apoptosis of leukemia cell line CML-T1 and normal peripheral blood lymphocytes (PBL). The poss...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178180/

データ提供：米国国立医学図書館（NLM）

Understanding the Role of ROS in Apoptosis

Cell death, like the fading of a desert flower, is a complex process. This study investigates the role of reactive oxygen species (ROS) in apoptosis, a programmed cell death pathway, induced by DNA-damaging agents and histone deacetylase inhibitors. The study explores the interplay between these agents and ROS, aiming to provide a deeper understanding of the mechanisms underlying cell death and the potential for therapeutic applications.

ROS: A Double-Edged Sword in Cell Death

This study explores the complex role of ROS in apoptosis, revealing the intricate interplay between these molecules and the mechanisms of cell death. The study highlights the potential for targeting ROS to modulate cell death pathways, potentially leading to new therapeutic strategies for treating diseases like cancer.

Navigating the Complexities of Cell Death

This research provides valuable insights into the complex world of cell death, exploring the role of ROS in apoptosis. The study's findings highlight the potential for targeting ROS to modulate cell death pathways, potentially leading to new therapeutic strategies for treating diseases like cancer.

Dr.Camel's Conclusion

This study delves into the complex world of cell death, investigating the role of reactive oxygen species (ROS) in apoptosis. The study's findings offer valuable insights into the intricate interplay between ROS and cell death pathways, potentially leading to new therapeutic strategies for treating diseases like cancer.
Date :
  1. Date Completed 2012-01-18
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

21949898

DOI: Digital Object Identifier

PMC3178180

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Languages

English

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