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5-Aminosalicylic acid suppositories in the maintenance of remission in idiopathic proctitis or proctosigmoiditis: a double-blind placebo-controlled clinical trial.

Author: BoscainoA, D'ArienzoA, D'ArmientoF P, GiannattasioF, LanciaC, MazzaccaG, PanareseA, QuattroneP

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

5-aminosalicylic acid (5-ASA) suppositories were found to be effective in maintaining remission of distal ulcerative colitis. The cumulative remission rate at the 12th month was 92% in the 5-ASA group and 21% in the placebo group. No side effects were observed.
Paper Details　
Original Abstract of the Article :
Thirty patients with distal ulcerative colitis in remission (17 proctitis, 13 proctosigmoiditis) were randomly given either 5-aminosalicylic acid (5-ASA) or placebo suppositories, 400 mg bid. During the 1-yr follow-up, patients were assessed clinically every month, and flexible sigmoidoscopy with a ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2202199

データ提供：米国国立医学図書館（NLM）

5-Aminosalicylic Acid: A Hopeful Remedy for Ulcerative Colitis

This research focuses on the inflammatory bowel disease ulcerative colitis, a debilitating condition characterized by inflammation of the colon. This study investigates the effectiveness of 5-aminosalicylic acid (5-ASA) suppositories in maintaining remission in patients with distal ulcerative colitis (proctitis and proctosigmoiditis). The researchers conducted a double-blind, placebo-controlled clinical trial to compare the efficacy of 5-ASA suppositories to a placebo.

5-ASA: A Powerful Ally in the Fight Against Ulcerative Colitis

The study demonstrated the effectiveness of 5-ASA suppositories in maintaining remission in patients with distal ulcerative colitis. The results showed a significantly higher cumulative remission rate at the 12th month in the 5-ASA group compared to the placebo group. The study also found that 5-ASA was well-tolerated, with no significant side effects reported. The findings support the use of 5-ASA suppositories as a safe and effective treatment for maintaining remission in distal ulcerative colitis.

Finding Relief in the Desert of Inflammatory Bowel Disease

This study offers a glimmer of hope for individuals struggling with ulcerative colitis. The findings suggest that 5-ASA can be a valuable tool in managing the condition and improving patients' quality of life. As Dr. Camel, I am reminded of the desert's resilience, where life finds ways to thrive even in challenging environments. Similarly, 5-ASA provides a beacon of hope in the midst of the inflammatory storm that is ulcerative colitis.

Dr.Camel's Conclusion

This study underscores the effectiveness of 5-ASA suppositories in maintaining remission in patients with distal ulcerative colitis. It offers a safe and effective treatment option that can help individuals achieve long-term relief and improve their quality of life. The study is a reminder that even in the face of challenging health conditions, hope and effective treatments can be found.

Date :
  1. Date Completed 1990-09-27
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2202199

DOI: Digital Object Identifier

2202199

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