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[Effects of Ginkgo biloba extract on anticoagulation and blood drug level of warfarin in healthy wolunteers].

Author: ZengRong, ZhouYulu

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Ginkgo biloba extract (GBE) had limited effects on the pharmacokinetics of warfarin, increasing C(max), AUC(0-144 min), AUC(0-infinity), t1/2, and decreasing CL(F), but did not significantly affect its pharmacodynamics or anticoagulant activity.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To study the effects of Ginkgo biloba extract (GBE) on the pharmacokinetics and pharmacodynamics of warfarin and observe the anticoagulant activity of GBE. METHOD: A randomized, double-blinded, placebo-controlled, two-way cross-over trial was conducted. Twelve healthy volunteers (sex rat...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/22097347

データ提供：米国国立医学図書館（NLM）

Ginkgo Biloba and Warfarin: A Careful Dance

Warfarin, a common blood thinner, can be like a delicate desert flower, requiring careful handling to avoid unintended consequences. Ginkgo biloba extract (GBE) is a popular herbal supplement that is like a curious desert plant, its interactions with other substances are not always fully understood. This study examined the effects of GBE on the pharmacokinetics and pharmacodynamics of warfarin. The authors aimed to investigate [主な目的] and determine if GBE could interact with warfarin in a way that might affect its effectiveness or safety. They found that [主要な発見], suggesting [研究分野における影響].

Ginkgo Biloba and Warfarin: A Gentle Touch

The research suggests that Ginkgo biloba extract may have limited effects on the pharmacokinetics of warfarin. It's like a desert plant that casts a subtle shadow on the delicate flower, without completely blocking its sunlight. However, the study found no significant effects on warfarin's pharmacodynamics, indicating that GBE doesn't seem to affect how the blood thinner works. This information is important for patients considering using GBE alongside warfarin, as it helps to ensure that the medication remains effective.

Navigating the Desert of Medication: A Collaborative Approach

If you're taking warfarin, it's essential to discuss any herbal supplements or medications you're considering with your healthcare provider. Just as a skilled desert guide knows which plants are safe to touch, your healthcare team can help you make informed decisions about your medications and avoid any potential complications.

Dr.Camel's Conclusion

This research provides valuable insights into the potential interactions between Ginkgo biloba extract and warfarin. It's like carefully observing the delicate balance between a desert plant and a fragile flower, ensuring that their growth and survival are not disrupted. The authors emphasize the need for ongoing research to fully understand the potential implications of GBE use in combination with other medications. This knowledge is crucial for ensuring the safety and effectiveness of treatment plans for patients.
Date :
  1. Date Completed 2011-12-06
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

22097347

DOI: Digital Object Identifier

22097347

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Languages

Chinese

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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