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Twenty-five year results of the national cancer institute randomized breast conservation trial.

Author: CamphausenKevin, DanTu, DanforthDavid N, GlatsteinEli, LippmanMarc E, LitaElena, SciutoLinda, ShihJoanna, SimoneNicole L, SmithSharon L, SwainSandra M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study reports on the 25-year outcomes of a randomized clinical trial comparing breast conservation therapy (BCT) with mastectomy (MRM) for early-stage breast cancer. The study found that long-term survival was similar between the two treatments, but BCT patients had a higher rate of isolated ipsilateral breast tumor recurrences (IBTRs).
Paper Details　
Original Abstract of the Article :
Breast conservation therapy (BCT) consisting of lumpectomy and postoperative radiation has become an accepted alternative to mastectomy (MRM) for the treatment of early stage breast cancer. We currently report the 25 year outcomes of a single institution, prospective, randomized clinical trial at th...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://pubmed.ncbi.nlm.nih.gov/22113254

データ提供：米国国立医学図書館（NLM）

Long-Term Outcomes of Breast Conservation Therapy

In the battle against breast cancer, researchers are constantly seeking new and effective treatments. This research examines the long-term outcomes of breast conservation therapy (BCT), a treatment option that has gained popularity as an alternative to mastectomy. The researchers explored the 25-year results of a randomized clinical trial, examining the long-term survival rates and potential risks associated with BCT.

A Long-Term Perspective: Navigating the Desert of Breast Cancer Treatment

This research offers a valuable long-term perspective on breast cancer treatment, like a guide leading a caravan through a vast desert. The researchers found that long-term survival rates were similar between BCT and mastectomy, highlighting the effectiveness of BCT as a treatment option. However, they also observed that BCT patients were at a slightly higher risk of developing isolated ipsilateral breast tumor recurrences (IBTRs), underscoring the importance of ongoing monitoring and potential need for additional interventions.

Balancing Benefits and Risks: A Wise Traveler’s Approach

This research highlights the importance of understanding the long-term implications of different treatment options. Just as a wise traveler in the desert considers the potential hazards and benefits of different routes, patients and their healthcare providers must carefully weigh the benefits and risks associated with different treatments. This research offers valuable insights into the long-term outcomes of BCT, helping patients and their providers to make informed decisions about the best course of treatment.

Dr.Camel's Conclusion

This research provides a valuable roadmap for navigating the desert of breast cancer treatment. While BCT has proven to be an effective option for many patients, it’s crucial to be aware of the potential long-term risks. By understanding these risks and carefully monitoring patients, we can ensure the best possible outcomes for those battling this challenging disease. As a camel connoisseur, I know that the journey through the desert can be unpredictable, but with careful planning and vigilance, we can find the most reliable and safe path to recovery.

Date :
  1. Date Completed 2012-05-22
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

22113254

DOI: Digital Object Identifier

NIHMS1725285

Related Literature

Article Analysis
・Effective treatment of breast cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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