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Safety and side effects of cannabidiol, a Cannabis sativa constituent.

Author: BergamaschiMateus Machado, CrippaJosé Alexandre S, QueirozRegina Helena Costa, ZuardiAntonio Waldo

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Cannabidiol (CBD), a non-psychoactive component of Cannabis, has various benefits including anxiety relief, anti-psychotic, anti-emetic, and anti-inflammatory properties. While research indicates CBD is generally safe at doses up to 1,500 mg/day, some studies suggest potential side effects such as liver enzyme inhibition, reduced cell viability, and impaired fertilization. Further research is needed to confirm these findings.
Paper Details　
Original Abstract of the Article :
Cannabidiol (CBD), a major nonpsychotropic constituent of Cannabis, has multiple pharmacological actions, including anxiolytic, antipsychotic, antiemetic and anti-inflammatory properties. However, little is known about its safety and side effect profile in animals and humans. This review describes i...See full text at original site
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引用元：
https://doi.org/10.2174/157488611798280924

データ提供：米国国立医学図書館（NLM）

Cannabidiol: A Promising Prospect with Potential Side Effects

Cannabidiol (CBD), a non-psychoactive component of Cannabis, has garnered significant attention for its potential therapeutic benefits. This study delves into the safety and side effects of CBD, examining its impact on both animals and humans. It compiles and analyzes a comprehensive dataset, providing a balanced perspective on this promising but understudied compound.

Navigating the CBD Landscape

The authors, like skilled cartographers charting an unexplored territory, carefully navigate the scientific literature, meticulously examining studies on CBD's effects. Their findings suggest that CBD, within certain dosage ranges, appears to be well-tolerated and non-toxic in non-transformed cells. However, they also note potential side effects, such as inhibition of hepatic drug metabolism and alterations in cell viability. The study serves as a reminder that even promising compounds may have unforeseen consequences.

Health Considerations and Practical Applications

The study highlights the importance of ongoing research to fully understand the safety profile of CBD. It emphasizes the need for caution when using CBD, especially in individuals with pre-existing medical conditions or those taking other medications. As with any therapeutic intervention, consultation with a healthcare professional is crucial to ensure safe and effective use.

Dr.Camel's Conclusion

Just as a camel navigates the arid desert, we must navigate the use of CBD with care and caution. The study underscores the need for further research to fully understand its potential benefits and risks. However, it also offers hope for the development of safe and effective CBD-based therapies in the future.

Date :
  1. Date Completed 2012-08-20
  2. Date Revised 2022-05-20
Further Info :

Pubmed ID

22129319

DOI: Digital Object Identifier

10.2174/157488611798280924

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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