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Crofelemer for the treatment of secretory diarrhea.

Author: CottreauJessica, CrutchleyRustin, GareyKevin W, TuckerAnne

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Crofelemer is a new antidiarrheal agent that targets two distinct channels in the GI tract. It is effective in secretory diarrhea, such as cholera, travelers' diarrhea and acute infectious diarrhea.
Paper Details　
Original Abstract of the Article :
Secretory diarrhea is a leading cause of morbidity and mortality worldwide. Crofelemer is a first-in-class antidiarrheal agent that simultaneously targets two distinct channels, the cystic fibrosis conductance regulator and calcium-activated chloride channel, responsible for chloride and fluid secre...See full text at original site
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引用元：
https://doi.org/10.1586/egh.11.87

データ提供：米国国立医学図書館（NLM）

Crofelemer for the Treatment of Secretory Diarrhea

Secretory diarrhea, characterized by excessive fluid loss, can be a debilitating condition. This research introduces crofelemer, a novel antidiarrheal agent derived from a tree found in the Amazon rainforest. Imagine crofelemer as a powerful, natural remedy discovered in a hidden oasis amidst the vast desert. This compound works by targeting specific channels in the gut that regulate fluid secretion, effectively putting a stop to the excessive water loss. The authors highlight the minimal toxicity of crofelemer and its efficacy in treating various types of secretory diarrhea, including cholera and traveler's diarrhea.

Crofelemer: A Promising New Treatment for Secretory Diarrhea

This research suggests that crofelemer could be a game-changer in treating secretory diarrhea. It offers a safe and effective alternative to traditional antidiarrheal medications. This is a welcome discovery, especially in regions where diarrhea is a major health concern.

A Natural Remedy from the Amazon

The discovery of crofelemer, derived from the Amazon rainforest, reminds us that nature holds a vast treasure trove of potential remedies. Like explorers uncovering hidden oases in the desert, researchers are constantly discovering new and effective natural solutions to medical problems.

Dr.Camel's Conclusion

This research points to the potential of crofelemer as a safe and effective treatment for secretory diarrhea. It's like a refreshing oasis in the desert of diarrhea treatments, offering hope to those struggling with this debilitating condition.

Date :
  1. Date Completed 2012-08-31
  2. Date Revised 2022-03-16
Further Info :

Pubmed ID

22149578

DOI: Digital Object Identifier

10.1586/egh.11.87

Related Literature

Article Analysis
・Side Effects of crofelemer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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