New insights into molecular mechanisms of sunitinib-associated side effects.

Author: Antón-AparicioLuis, Aparicio-GallegoGuadalupe, BlancoMoisés, FigueroaAngélica, García-CampeloRosario, Grande-PulidoEnrique, Valladares-AyerbesManuel

Paper Details 
Original Abstract of the Article :
The introduction of targeted therapy represents a major advance in the treatment of tumor progression. Targeted agents are a novel therapeutic approach developed to disrupt different cellular signaling pathways. The tyrosine kinase inhibitor sunitinib specifically blocks multiple tyrosine kinase rec...See full text at original site
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引用元:
https://doi.org/10.1158/1535-7163.MCT-10-1124

データ提供:米国国立医学図書館(NLM)

Unveiling the Side Effects of Targeted Therapy: A Journey into the Molecular Desert

The desert of medical research is vast and ever-expanding, revealing new frontiers in the fight against disease. Targeted therapy, like a pioneering expedition, has opened up new possibilities for cancer treatment. This study focuses on sunitinib, a powerful drug used to combat various cancers, and explores the intricate mechanisms behind its sometimes unexpected side effects.

The Intricate Network of Molecular Pathways

The researchers, like skilled desert navigators, delved into the molecular mechanisms that underpin sunitinib’s actions. They discovered that while sunitinib effectively targets specific pathways involved in tumor growth, it can also have unintended consequences, like a ripple effect across the desert sands. This study sheds light on the complex interactions between drugs and the body’s intricate network of molecules.

The Quest for Precision Medicine

This research underscores the importance of precision medicine, where treatment is tailored to the individual patient’s genetic and molecular profile. It’s like a careful journey across the desert, recognizing that every individual is unique and responds differently to treatment. This study emphasizes the need for continued research to better understand the nuances of drug interactions and minimize unwanted side effects.

Dr. Camel’s Conclusion

This study, like a captivating desert odyssey, highlights the intricate complexities of modern medicine. It reminds us that the pursuit of effective treatment requires a deep understanding of the body’s molecular mechanisms, a commitment to individualization, and a dedication to ongoing research. As we continue to navigate the ever-changing landscape of medical science, we must embrace a spirit of exploration and a commitment to the well-being of all.
Date :
  1. Date Completed 2012-05-11
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

22161785

DOI: Digital Object Identifier

10.1158/1535-7163.MCT-10-1124

Related Literature

SNS
PICO Info
in preparation
Languages

English

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