Acute dapsone overdose: the effects of continuous veno-venous haemofiltration on the elimination of dapsone.

Author: AnsteyC M, EdsteinM D, GortonC J, MasurkarV A

Paper Details 
Original Abstract of the Article :
A 15-year-old girl presented after intentional ingestion of dapsone (7.2 g) and small quantities of azathioprine, methotrexate and prednisolone. The resulting methaemoglobinaemia and lactic acidosis persisted despite treatment with methylene blue, multiple-dose activated charcoal and ascorbic acid. ...See full text at original site
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引用元:
https://doi.org/10.1177/0310057X1103900624

データ提供:米国国立医学図書館(NLM)

Dapsone Overdose: Navigating the Desert of Toxicity

Dapsone, a medication used to treat various conditions, can pose a significant risk of toxicity if ingested in excessive amounts. This case study takes us on a journey through the desert of dapsone overdose, a dangerous landscape where the consequences of drug toxicity can be severe. The study explores the use of continuous veno-venous haemofiltration, a process akin to a desert oasis providing vital hydration and purification, to effectively remove dapsone from the body.

Haemofiltration: A Cleansing Oasis in the Desert of Toxicity

The study demonstrates that continuous veno-venous haemofiltration can successfully reduce toxic dapsone concentrations in the blood, a critical intervention in navigating the dangerous desert of overdose. This technique, akin to using a natural filter to purify contaminated water, plays a vital role in restoring balance and mitigating the harmful effects of dapsone toxicity.

Navigating the Desert of Overdose: A Call for Vigilance

This case study underscores the importance of vigilance and timely intervention in managing drug overdose, a treacherous journey through a toxic desert. The success of haemofiltration in this case highlights the crucial role of advanced medical interventions in mitigating the harmful consequences of drug toxicity, providing a pathway towards recovery.

Dr.Camel's Conclusion

The desert of drug overdose is a perilous landscape, where the risk of toxicity can be life-threatening. This case study serves as a reminder of the importance of careful medication management and timely intervention in the event of an overdose. The use of haemofiltration, a vital oasis in this challenging journey, underscores the importance of advanced medical treatments in mitigating the devastating effects of drug toxicity, offering a beacon of hope for individuals navigating this treacherous terrain.

Date :
  1. Date Completed 2012-01-03
  2. Date Revised 2019-03-19
Further Info :

Pubmed ID

22165371

DOI: Digital Object Identifier

10.1177/0310057X1103900624

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Languages

English

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