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Acute dapsone overdose: the effects of continuous veno-venous haemofiltration on the elimination of dapsone.
Author: AnsteyC M, EdsteinM D, GortonC J, MasurkarV A
Original Abstract of the Article :
A 15-year-old girl presented after intentional ingestion of dapsone (7.2 g) and small quantities of azathioprine, methotrexate and prednisolone. The resulting methaemoglobinaemia and lactic acidosis persisted despite treatment with methylene blue, multiple-dose activated charcoal and ascorbic acid. ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1177/0310057X1103900624
データ提供:米国国立医学図書館(NLM)
Dapsone Overdose: Navigating the Desert of Toxicity
Dapsone, a medication used to treat various conditions, can pose a significant risk of toxicity if ingested in excessive amounts. This case study takes us on a journey through the desert of dapsone overdose, a dangerous landscape where the consequences of drug toxicity can be severe. The study explores the use of continuous veno-venous haemofiltration, a process akin to a desert oasis providing vital hydration and purification, to effectively remove dapsone from the body.
Haemofiltration: A Cleansing Oasis in the Desert of Toxicity
The study demonstrates that continuous veno-venous haemofiltration can successfully reduce toxic dapsone concentrations in the blood, a critical intervention in navigating the dangerous desert of overdose. This technique, akin to using a natural filter to purify contaminated water, plays a vital role in restoring balance and mitigating the harmful effects of dapsone toxicity.
Navigating the Desert of Overdose: A Call for Vigilance
This case study underscores the importance of vigilance and timely intervention in managing drug overdose, a treacherous journey through a toxic desert. The success of haemofiltration in this case highlights the crucial role of advanced medical interventions in mitigating the harmful consequences of drug toxicity, providing a pathway towards recovery.
Dr.Camel's Conclusion
The desert of drug overdose is a perilous landscape, where the risk of toxicity can be life-threatening. This case study serves as a reminder of the importance of careful medication management and timely intervention in the event of an overdose. The use of haemofiltration, a vital oasis in this challenging journey, underscores the importance of advanced medical treatments in mitigating the devastating effects of drug toxicity, offering a beacon of hope for individuals navigating this treacherous terrain.
Date :
- Date Completed 2012-01-03
- Date Revised 2019-03-19
Further Info :
Related Literature
English
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