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Safety and immunogenicity of a modified process hepatitis B vaccine in healthy neonates.

Author: AtkinsBarbara M, BhuyanPrakash K, LiskaVladimir, MartinJason C, McCarsonBarbara J, MinerviniGianmaria, NadigKarin B, ReisingerKeith S, SchödelFlorian P, StekJon E

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the safety and immunogenicity of a modified process hepatitis B vaccine (mpHBV) in newborn infants. The mpHBV was previously shown to have an acceptable safety and immunogenicity profile in young adults.
Paper Details　
Original Abstract of the Article :
A manufacturing process using a modified adjuvant was developed to optimize the consistency and immunogenicity for recombinant hepatitis B vaccine (control: RECOMBIVAX-HB™). This modified process hepatitis B vaccine (mpHBV), which was previously shown to have an acceptable safety and immunogenicity ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.vaccine.2011.12.095

データ提供：米国国立医学図書館（NLM）

A New Dawn for Hepatitis B Vaccination in Neonates: Safety and Immunogenicity of a Modified Process Vaccine

The fight against infectious diseases is an ongoing battle, and hepatitis B is a formidable foe. This study investigates the safety and immunogenicity of a modified process hepatitis B vaccine (mpHBV), designed to enhance consistency and immunogenicity, in newborn infants. The researchers aimed to evaluate the vaccine's potential in this vulnerable population.

The study revealed that mpHBV exhibits an acceptable safety and immunogenicity profile in newborn infants. This promising finding could significantly impact the global effort to protect infants from hepatitis B, a potentially life-threatening infection.

A Safe and Effective Option for Protecting Infants from Hepatitis B

The development of a safe and effective hepatitis B vaccine for newborns is a major milestone in public health. This research offers a new avenue for protecting infants from this serious disease, potentially leading to improved global health outcomes.

Protecting the Most Vulnerable: A Legacy of Health

Hepatitis B is a significant health threat, particularly for infants, who are more susceptible to severe complications. This study provides a beacon of hope, offering a new strategy for safeguarding the health of future generations by preventing hepatitis B infection in newborns.

Dr. Camel's Conclusion

Just as a desert oasis offers refuge for weary travelers, this research provides a safe haven for newborns, shielding them from the threat of hepatitis B. The development of a safe and effective vaccine for infants is a testament to the relentless pursuit of improving global health and ensuring a brighter future for all.

Date :
  1. Date Completed 2012-05-23
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

22227229

DOI: Digital Object Identifier

10.1016/j.vaccine.2011.12.095

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・Side Effects of hepatitis b vaccine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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