Daytime wakefulness following a bedtime oral dose of zolpidem 20 mg, flunitrazepam 2 mg and placebo.

Author: BensimonG, ForetJ, LacomblezL, SimonP, ThiercelinJ F, WarotD

Paper Details 
Original Abstract of the Article :
1. The effects of zolpidem 20 mg, flunitrazepam 2 mg and placebo, administered at bed time, were studied in 12 healthy young male volunteers. 2. The assessments included, at awakening, subjective ratings of overnight sleep, cognitive function, psychomotor performance (digit symbol substitution, choi...See full text at original site
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引用元:
https://doi.org/10.1111/j.1365-2125.1990.tb03798.x

データ提供:米国国立医学図書館(NLM)

Zolpidem vs. Flunitrazepam: Navigating the Desert of Sleep

Sleep is a vital oasis in the desert of our daily lives. This research delves into the effects of two popular sleep medications, zolpidem and flunitrazepam, on daytime wakefulness. The study, conducted on healthy young male volunteers, aimed to assess the impact of these drugs on sleep quality, cognitive function, and daytime alertness. The researchers found that both drugs improved sleep initiation, but flunitrazepam had lingering effects on cognitive performance and daytime sleepiness. Zolpidem, however, appeared to leave subjects unimpaired, suggesting a more favorable profile for maintaining daytime alertness. This research provides valuable insights into the potential benefits and drawbacks of these commonly prescribed sleep medications.

A Balancing Act: Sleep and Wakefulness

The study revealed that flunitrazepam, while improving sleep onset, had a notable impact on daytime performance. This highlights the delicate balance between achieving restful sleep and maintaining optimal cognitive function. On the other hand, zolpidem seemed to offer a more balanced approach, improving sleep without significantly impairing daytime alertness. This finding suggests that zolpidem might be a more suitable choice for individuals who require a medication that promotes sleep without affecting their daytime activities.

Navigating the Sleep Desert

Sleep is essential for our physical and mental well-being. While sleep medications can be helpful in addressing specific sleep disorders, it's crucial to consult with a healthcare professional to determine the most appropriate treatment option. This research underscores the importance of considering the potential impact of sleep medications on both sleep quality and daytime function. Remember, like a wise camel, we should strive to find a balance in our lives, embracing both the serenity of sleep and the energy of wakefulness.

Dr. Camel's Conclusion

This study, like a desert caravan carefully navigating a treacherous landscape, highlights the challenges of finding the right medication for sleep. It's crucial to understand the potential effects of these drugs on both sleep and wakefulness, making informed decisions about our sleep health. As Dr. Camel, I remind you, "Sleep, like a cool oasis, can rejuvenate us. But, we must also navigate the desert of wakefulness with clarity and focus."

Date :
  1. Date Completed 1990-12-04
  2. Date Revised 2019-05-10
Further Info :

Pubmed ID

2223425

DOI: Digital Object Identifier

10.1111/j.1365-2125.1990.tb03798.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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