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Effect of TNF inhibitors on lipid profile in rheumatoid arthritis: a systematic review with meta-analysis.
Author: BarnetcheThomas, CombeBernard, DaurèsJean-Pierre, DaïenClaire Immediato, DunyYohan, MorelJacques
Original Abstract of the Article :
Patients with rheumatoid arthritis (RA) are at increased risk of cardiovascular disease. Lipid changes related to inflammation have been described in RA. Tumour necrosis factor α (TNFα) inhibitor (TNFi) treatment is effective in controlling inflammation and decreasing the number of cardiovascular ev...See full text at original site
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1136/annrheumdis-2011-201148
データ提供:米国国立医学図書館(NLM)
TNF Inhibitors and Lipid Profiles: Navigating the Complexities of Rheumatoid Arthritis
The world of inflammatory diseases is a complex one, with researchers constantly seeking new ways to manage the debilitating effects of conditions like rheumatoid arthritis (RA). This systematic review delves into the impact of TNF inhibitors, a type of medication used to control inflammation, on lipid profiles in patients with RA. The study examines the relationship between inflammation and lipid changes, much like a desert traveler studying the subtle shifts in the dunes over time.
TNF Inhibitors and Lipid Changes: A Balancing Act
The study finds that TNF inhibitors, while effective in controlling inflammation, may also have an impact on lipid profiles. This finding, like a shifting sand dune, highlights the need for careful monitoring of lipid levels during TNF inhibitor therapy.
Navigating the Treatment Landscape: Balancing Inflammation Control and Cardiovascular Risk
This research reinforces the importance of considering the potential cardiovascular effects of TNF inhibitors in managing RA. Healthcare providers must work closely with patients to monitor lipid levels and adjust treatment strategies accordingly, ensuring a careful balance between managing inflammation and minimizing cardiovascular risk.
Dr.Camel's Conclusion
This systematic review provides valuable insights into the complex relationship between TNF inhibitors, lipid profiles, and cardiovascular risk in patients with RA. By shedding light on the potential for lipid changes associated with TNF inhibitor therapy, the study underscores the importance of careful monitoring and individualized treatment strategies. This research encourages continued exploration of the interplay between inflammation, lipid metabolism, and cardiovascular health in the management of RA.
Date :
- Date Completed 2012-07-03
- Date Revised 2022-03-18
Further Info :
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