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Paper Details

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Paper Details

Orthostatic hypotension induced by postural change in the rat (tilt test).

Author: GuillaumePhilippe, HervéStéphane, LacroixPierre, PicardSandra

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Postural-change-induced (orthostatic) hypotension is a side effect that can occur with drugs that dampen sympathetic reflex activity. This study describes a procedure for evaluating the effects of test substances on blood pressure and heart rate changes in an anesthetized rat during a tilting challenge.

Paper Details　

Original Abstract of the Article :

Postural-change-induced (orthostatic) hypotension is defined as an excessive drop in arterial blood pressure occurring when moving toward an upright position. This side effect, which may limit the therapeutic use of some agents, can occur with drugs, such as adrenoceptor blockers and vasodilators, t...See full text at original site

Dr.Camel's Paper Summary Blog

in preparation

Date :

Date Completed 2012-03-30
Date Revised 2016-10-21

Further Info :

Pubmed ID

DOI: Digital Object Identifier

10.1002/0471141755.ph0545s40

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Languages

English

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