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Clinical and instrumental assessment of the effects of a new product based on hydroxypropyl chitosan and potassium azeloyl diglycinate in the management of rosacea.

Author: AbrilElva, BerardescaEnzo, CaseriniMaurizio, GuglielminiGiancarlo, IorizzoMatilde, PalmieriRenata, PiérardGérald E

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A cream containing 5% potassium azeloyl diglycinate and 1% hydroxypropyl chitosan effectively reduced erythema and other symptoms in patients with rosacea. The cream was well tolerated and showed promise for controlling signs and symptoms of rosacea.
Paper Details　
Original Abstract of the Article :
BACKGROUND:   Rosacea is a chronic inflammatory skin disease affecting mostly facial skin. Its origin is multifactorial. Important steps in its treatment are avoidance of any triggering factor and control of skin inflammation. AIM:   To assess the benefit of topical applications of a new product (P...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488300/

データ提供：米国国立医学図書館（NLM）

A New Approach to Rosacea Management: Combining Hydroxypropyl Chitosan and Potassium Azeloyl Diglycinate

The study of [rosacea] is a journey into the complexities of skin inflammation, a condition that can significantly impact an individual's appearance and self-esteem. This study investigates the efficacy and tolerability of a new topical cream (P-3075) containing 5% potassium azeloyl diglycinate (PAD) and 1% hydroxypropyl chitosan (HPCH) in the treatment of rosacea.

A Promising Combination: P-3075's Effectiveness in Reducing Erythema and Skin Inflammation

The study found that P-3075 cream was effective in reducing erythema, a key symptom of rosacea, both objectively and clinically. This suggests that the combination of PAD and HPCH may offer a promising approach to managing rosacea symptoms.

A Gentle Approach: P-3075's Tolerability and Potential for Long-Term Use

The study also noted that P-3075 cream was well-tolerated by patients. This finding, coupled with its effectiveness in reducing erythema and other rosacea symptoms, suggests that P-3075 could be a valuable addition to the treatment arsenal for individuals with rosacea.

Dr.Camel's Conclusion

Rosacea can be a frustrating condition, but this study offers a glimmer of hope with the introduction of a new cream that shows promising results. Just as a desert traveler seeks relief from the harsh sun, individuals with rosacea can find solace in P-3075's ability to reduce erythema and inflammation, offering a path towards clearer and healthier skin.

Date :
  1. Date Completed 2012-07-05
  2. Date Revised 2023-11-05
Further Info :

Pubmed ID

22360333

DOI: Digital Object Identifier

PMC3488300

Related Literature

Article Analysis
・Effective treatment of rosacea
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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