Investigation of the cochlear effects of intratympanic steroids administered following acoustic trauma.

Author: CakirOzgur, DereHuseyin, EnsariSerdar, GurgenSeren Gulsen, KoseogluSabri, OzcanKursat Murat, OzdasTalih, OzdoganFatih

Paper Details 
Original Abstract of the Article :
OBJECTIVES/HYPOTHESIS: To electrophysiologically and histomorphologically demonstrate the effects of intratympanic corticosteroids administered following an acoustic trauma on cochlear hair cells. METHODS: The trial was performed on 16 Wistar albino rats. The rats underwent distortion product otoac...See full text at original site
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引用元:
https://doi.org/10.1002/lary.23185

データ提供:米国国立医学図書館(NLM)

Protecting the Cochlea: A Novel Approach to Acoustic Trauma

Acoustic trauma, like a sudden desert sandstorm, can wreak havoc on the delicate structures of the inner ear, leading to hearing loss. This study investigates the potential of intratympanic steroid injections to protect the cochlea, the part of the inner ear responsible for hearing, from the damaging effects of noise exposure. The researchers, like skilled desert healers, sought to determine if corticosteroids could prevent or reduce cochlear damage and hearing loss after acoustic trauma.

A Shield Against Sound Damage

The study found that intratympanic methylprednisolone injections were effective in reducing cochlear hair cell loss, a key indicator of acoustic trauma. The findings suggest that early intervention with corticosteroids may help to protect the cochlea from noise-induced damage.

Implications for Hearing Protection and Treatment

This research offers a potential avenue for developing new treatments for acoustic trauma, potentially minimizing the impact of noise exposure on hearing health.

Dr.Camel's Conclusion

This study provides a glimmer of hope in the desert of acoustic trauma. It suggests that intratympanic steroid injections may offer a protective shield against the damaging effects of noise, potentially preserving hearing and improving quality of life.

Date :
  1. Date Completed 2012-05-29
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

22374513

DOI: Digital Object Identifier

10.1002/lary.23185

Related Literature

SNS
PICO Info
in preparation
Languages

English

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