Paper Details 
Original Abstract of the Article :
Effects of 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3), natural ligand of the VDR, on the fates of adefovir dipivoxil (P-gp substrate) and its metabolites, mono(POM)-PMEA and adefovir (MRP4 substrate), were investigated in Caco-2 cells. After 1,25(OH)2D3-treatment, higher apical efflux of adefovir was o...See full text at original site
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引用元:
https://doi.org/10.1016/j.ejps.2012.02.018

データ提供:米国国立医学図書館(NLM)

The Impact of Vitamin D on Adefovir Dipivoxil: A Journey Through the Desert of Drug Metabolism

The human body is a complex desert, with intricate pathways and mechanisms governing drug metabolism. This research, like a curious explorer venturing into the unknown, investigates the impact of [research methodology] to explore [research objectives]. The authors discovered [main findings] highlighting the potential role of vitamin D in drug interactions. The results demonstrate the [remarkable results or significance] of vitamin D on the transport and metabolism of adefovir dipivoxil.

Vitamin D and Adefovir Dipivoxil: A New Perspective on Drug Interactions

This research, like a map revealing hidden springs, provides valuable insights into the complex interplay between vitamin D and drug metabolism. The findings suggest that [social implications], highlighting the importance of considering the potential impact of vitamin D on drug efficacy and safety.

Navigating the Desert of Drug Interactions

As we journey through the vast desert of drug metabolism, it is crucial to understand the factors that can influence drug activity. This research, like a beacon of knowledge, sheds light on the potential impact of vitamin D on the transport and metabolism of adefovir dipivoxil, providing a deeper understanding of drug interactions and their implications for patient care.

Dr. Camel's Conclusion

This research, like a well-placed oasis in the desert of drug metabolism, provides valuable insights into the complex interaction between vitamin D and adefovir dipivoxil. It highlights the importance of considering the potential impact of vitamin D on drug efficacy and safety and underscores the need for further research in this area.

Date :
  1. Date Completed 2012-08-02
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

22387228

DOI: Digital Object Identifier

10.1016/j.ejps.2012.02.018

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Languages

English

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