Paper Details

  1. Home
  2. Paper Details

Local and systemic safety of intranasal corticosteroids.

Author: MosgesR, SastreJ

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Intranasal corticosteroids (INCs) are effective and safe treatments for allergic rhinitis, rhinosinusitis, and nasal polyps. While some concerns exist about systemic side effects, a review of the literature indicates that INCs primarily have local side effects, such as nasal irritation and epistaxis, and have a favorable safety profile.
Paper Details　
Original Abstract of the Article :
The safety and efficacy of intranasal corticosteroids (INCs) are well established for the management of allergic rhinitis, rhinosinusitis, and nasal polyps. As seen in numerous studies, INCs demonstrate markedly reduced systemic bioavailability compared with oral and even inhaled corticosteroids and...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/22448448

データ提供：米国国立医学図書館（NLM）

Safety of Intranasal Corticosteroids

Intranasal corticosteroids (INCs) are widely used to manage allergic rhinitis, rhinosinusitis, and nasal polyps. This study examines the safety profile of INCs, addressing concerns about potential systemic side effects. The researchers conducted a comprehensive review of the published literature to assess the evidence regarding the safety of these medications.

Addressing Concerns about Systemic Side Effects

The study concludes that the available evidence does not support concerns about systemic side effects from INCs. The researchers found that INCs have a favorable safety profile, with a low incidence of mostly mild and transient local side effects.

Reassurance for Healthcare Providers and Patients

This study provides reassurance for healthcare providers and patients about the safety of INCs. The findings suggest that these medications can be safely used to manage a variety of nasal conditions, offering effective relief with minimal risk of systemic adverse events.

Dr. Camel's Conclusion

This study is like a cool breeze on a hot day, dispelling the myths and worries surrounding the use of INCs. The researchers' thorough review of the literature provides strong evidence for the safety of these medications. This research offers valuable insights into the benefits and risks of INCs, providing healthcare providers and patients with a clear understanding of these widely used medications.

Date :
  1. Date Completed 2012-06-15
  2. Date Revised 2013-07-31
Further Info :

Pubmed ID

22448448

DOI: Digital Object Identifier

22448448

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.