Comparison of the efficacy and safety of fixed-dose amlodipine/losartan and losartan in hypertensive patients inadequately controlled with losartan: a randomized, double-blind, multicenter study.

Author: ChoSeung Yun, ChoiYoung Jin, HongBum-Kee, KimKi Sik, ParkChang Gyu, YangJoo Young, YoonHo Joong, YoonJeong Han, YoonMyeong Ho

Paper Details 
Original Abstract of the Article :
BACKGROUND: Fixed-dose combination drugs may enhance blood pressure (BP) goal attainment through complementary effects and reduced side effects, which leads to better compliance. OBJECTIVE: This study aimed to evaluate the efficacy and safety profiles of once-daily combination amlodipine/losartan v...See full text at original site
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引用元:
https://doi.org/10.2165/11597410-000000000-00000

データ提供:米国国立医学図書館(NLM)

Fixed-Dose Amlodipine/Losartan: A Synergistic Approach to Blood Pressure Control

High blood pressure (hypertension) is like a relentless desert wind, eroding the body's health over time. This study compared the efficacy and safety of fixed-dose amlodipine/losartan combination therapy with losartan alone in patients with hypertension inadequately controlled by losartan. It's like trying to find the best way to build a shelter in the desert, utilizing different materials and techniques to achieve optimal protection.

Amlodipine/Losartan: A Superior Solution for Blood Pressure Control

The researchers found that the fixed-dose combination therapy achieved significantly greater reductions in blood pressure and a higher response rate compared to losartan alone. It's like finding a combination of materials that provides greater strength and stability for a shelter in the desert. The findings suggest that combining amlodipine and losartan may offer a more effective approach to blood pressure management.

Navigating the Desert of Hypertension

This research emphasizes the importance of finding the right combination of medications to effectively manage hypertension. It's like a camel caravan carefully choosing its route based on the specific terrain and challenges. The researchers encourage further investigation to explore the optimal combinations and dosages for different patients.

Dr. Camel's Conclusion

High blood pressure, like a persistent desert wind, can wreak havoc on our health. This research highlights the potential of fixed-dose amlodipine/losartan combination therapy as a more effective approach to blood pressure management. Like a wise camel navigating a challenging desert, we must continue to explore new strategies to combat this common health issue and improve patient outcomes.

Date :
  1. Date Completed 2012-09-10
  2. Date Revised 2022-03-16
Further Info :

Pubmed ID

22462558

DOI: Digital Object Identifier

10.2165/11597410-000000000-00000

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PICO Info
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Languages

English

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