Paper Details

  1. Home
  2. Paper Details

Infant safety during and after maternal valacyclovir therapy in conjunction with antiretroviral HIV-1 prophylaxis in a randomized clinical trial.

Author: DrakeAlison L, FarquharCarey, John-StewartGrace, KiarieJames, RichardsonBarbra A, RoxbyAlison C, WaldAnna

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Valacyclovir, an acyclovir prodrug, is compatible with pregnancy and breastfeeding. However, the safety profile of prolonged infant and maternal exposure to acyclovir in the context of antiretrovirals (ARVs) for prevention of mother-to-child HIV-1 transmission (PMTCT) has not been described.
Paper Details　
Original Abstract of the Article :
Maternal administration of the acyclovir prodrug valacyclovir is compatible with pregnancy and breastfeeding. However, the safety profile of prolonged infant and maternal exposure to acyclovir in the context of antiretrovirals (ARVs) for prevention of mother-to-child HIV-1 transmission (PMTCT) has n...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324503/

データ提供：米国国立医学図書館（NLM）

Valacyclovir: A Safe Option for HIV-Positive Mothers and Infants

The well-being of mothers and their infants is a priority in healthcare. This study explores the safety of maternal valacyclovir therapy, a medication used to prevent the transmission of herpes simplex virus, in conjunction with antiretroviral HIV-1 prophylaxis.

Valacyclovir: A Safe and Effective Treatment

The research shows that maternal administration of valacyclovir is compatible with pregnancy and breastfeeding, with no significant adverse effects on infant health. This study is like finding a safe and secure oasis in the desert of pregnancy and childbirth, offering a reassuring solution for HIV-positive mothers and their infants.

Improving Maternal and Infant Health

This research provides valuable insights into the safety of valacyclovir for HIV-positive mothers and their infants, contributing to better maternal and infant health outcomes.

Dr.Camel's Conclusion

The study on valacyclovir is like discovering a peaceful oasis in the desert of pregnancy and childbirth, offering a safe and effective treatment option for HIV-positive mothers and their infants. This research is a testament to the ongoing efforts to ensure the well-being of mothers and their children in challenging circumstances.

Date :
  1. Date Completed 2012-08-20
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

22509337

DOI: Digital Object Identifier

PMC3324503

Related Literature

Article Analysis
・Side Effects of valacyclovir
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.