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Effect of calcium channel blockers on experimentally induced seizures in rats.
Author: DavidJ, JosephT, KamalJ A, NadigR S
Original Abstract of the Article :
Chemically different classes of calcium channel blockers were examined in rats for their effects on behavior, tolerability and protection against maximal electroshock seizures (MES) and pentylenetetrazol (PTZ) induced seizures. In MES test at doses (mg/kg, ip) that were devoid of side effects, felod...See full text at original site
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/2272645
データ提供:米国国立医学図書館(NLM)
Calcium Channel Blockers: A New Approach to Seizure Control
This study explores the potential of calcium channel blockers to combat seizures, a condition that can be as unpredictable as a desert sandstorm. The study examines the effects of different classes of calcium channel blockers on chemically induced seizures in rats, finding that some of these drugs showed promising anticonvulsant activity. It's like finding a desert plant with unique properties that can help tame the wild winds.
Calcium Channel Blockers: A Potential New Frontier in Epilepsy Treatment
The study highlights the potential of calcium channel blockers as adjuvant therapeutic agents for epilepsy, particularly for patients who are resistant to conventional antiepileptic medications. It's like discovering a new tool in the desert explorer's kit, offering a potential solution for a challenging problem.
Calcium Channel Blockers: A Balancing Act in the Desert
While some calcium channel blockers showed promise in reducing seizures, the study also noted that some were associated with side effects, emphasizing the need for careful consideration and a balanced approach. It's like navigating a desert with both scorching sun and treacherous sand dunes, requiring careful attention to both risks and rewards.
Dr.Camel's Conclusion
This research opens up new possibilities for treating seizures, like a desert explorer stumbling upon a hidden oasis. Calcium channel blockers may offer a valuable addition to the arsenal of treatments for epilepsy, but further research is needed to fully understand their potential and navigate the challenging terrain of side effects.
Date :
- Date Completed 1991-02-28
- Date Revised 2013-11-21
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English
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