Salmeterol and fluticasone in young children with multiple-trigger wheeze.

Author: CsonkaPeter, KajosaariMerja, KlemolaTimo, MalmbergL Pekka, MäkeläMika J, PelkonenAnna S

Paper Details 
Original Abstract of the Article :
BACKGROUND: Treatment guidelines recommend using an inhaled corticosteroid (ICS) plus a long-acting β(2)-agonist (LABA) for childhood asthma when the symptoms are not controlled by ICS alone, but the appropriate use of LABAs in children continues to be debated. OBJECTIVE: To compare the efficacy of...See full text at original site
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引用元:
https://doi.org/10.1016/j.anai.2012.05.006

データ提供:米国国立医学図書館(NLM)

Salmeterol and Fluticasone in Young Children with Wheeze

This study tackles the complex issue of asthma treatment in young children, particularly those with multiple-trigger wheeze. The research explores the efficacy of a combination therapy involving salmeterol, a long-acting beta-agonist, and fluticasone propionate, an inhaled corticosteroid, compared to individual treatment with either drug. The study aims to provide evidence-based guidance on the appropriate use of LABAs in young children with asthma.

Comparative Efficacy in Treating Wheeze

The study design involves a randomized controlled trial, a robust method for comparing the effectiveness of different treatments. The study compares the effects of combined salmeterol-fluticasone therapy, fluticasone propionate alone, and salmeterol alone in children aged 4 to 7 years with multiple-trigger wheeze. This allows for a clear and objective assessment of the benefits and risks associated with each treatment approach.

Navigating Asthma Treatment in Children

This study offers valuable insights into the appropriate treatment strategies for children with asthma. The findings suggest that salmeterol-fluticasone and fluticasone alone are comparable in their effectiveness, with a slight advantage in lung function improvement observed with the combination therapy. This research provides guidance for healthcare professionals in managing asthma in young children, offering a more informed approach to improving respiratory health.

Dr. Camel's Conclusion

This study is like exploring a vast desert of asthma treatment options, seeking the most effective solution for young children. The research highlights the potential benefits of a combination therapy, offering a wider range of options to address the unique needs of these patients. This study underscores the importance of continually adapting treatment strategies based on the latest research and clinical evidence.
Date :
  1. Date Completed 2012-09-06
  2. Date Revised 2017-11-16
Further Info :

Pubmed ID

22727160

DOI: Digital Object Identifier

10.1016/j.anai.2012.05.006

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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