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Pharmacokinetics of quinapril and its active metabolite quinaprilat during continuous ambulatory peritoneal dialysis.
Author: HorvathA M, OlsonS C, PosvarE L, StarmannB, SwartzR D
Original Abstract of the Article :
The pharmacokinetics of quinapril, a novel angiotensin converting enzyme (ACE) inhibitor, and its active metabolite, quinaprilat, were determined following a single 20-mg oral dose of quinapril in six patients with chronic renal failure maintained on continuous ambulatory peritoneal dialysis (CAPD)....See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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引用元:
https://doi.org/10.1002/j.1552-4604.1990.tb01857.x
データ提供:米国国立医学図書館(NLM)
Quinapril for Chronic Renal Failure Patients on Continuous Ambulatory Peritoneal Dialysis (CAPD)
The [management of chronic renal failure] is a complex and challenging task, often requiring the use of medications to manage various complications. This study investigates the [pharmacokinetics of quinapril] in patients with chronic renal failure who are undergoing [continuous ambulatory peritoneal dialysis (CAPD)].
The researchers found that quinapril was well tolerated by CAPD patients, with mild and transient side effects. The drug was effectively absorbed and eliminated from the body, with a prolonged half-life of its active metabolite, quinaprilat. The study also found that blood pressure reduction was observed in most patients, suggesting that quinapril could be a safe and effective treatment option for patients with chronic renal failure on CAPD.
Quinapril: A Potential Oasis in the Desert of Chronic Renal Failure
This study highlights the potential benefits of quinapril for patients with chronic renal failure on CAPD. It shows that the drug can be safely administered and effectively manage blood pressure, offering a potential oasis in the desert of chronic kidney disease management. While further research is needed to fully understand its long-term effects, this study provides a promising step forward for improving the lives of patients with chronic renal failure.
A Journey Through the Desert of Chronic Renal Failure: Optimizing Treatment
This study reminds us that finding the right medication and dosage for patients with chronic renal failure can be like finding a hidden well in the desert. It's a journey that requires careful consideration of individual patient factors and ongoing monitoring to ensure optimal treatment outcomes. This research provides valuable insights into the potential of quinapril to improve the management of chronic renal failure, offering hope for a smoother and more comfortable journey for patients.
Dr.Camel's Conclusion
This study is like a caravan navigating the vast desert of chronic renal failure. The findings suggest that quinapril can be a safe and effective treatment option for patients on CAPD, offering hope for improved blood pressure control and a better quality of life. This is a testament to the ongoing efforts to find solutions for managing this challenging condition.
Date :
- Date Completed 1991-02-22
- Date Revised 2019-08-24
Further Info :
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