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Long-term effects of pneumococcal conjugate vaccine on nasopharyngeal carriage of S. pneumoniae, S. aureus, H. influenzae and M. catarrhalis.

Author: BogaertDebby, BruinJacob P, PrevaesSabine M P J, SandersElisabeth A M, SpijkermanJudith, VeenhovenReinier H, Wijmenga-MonsuurAlienke J, van GilsElske J M, van den DobbelsteenGermie P J M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

After the introduction of PCV-7, persistently higher nasopharyngeal prevalence rates of S. aureus and H. influenzae were observed among young children and their parents. These findings may have implications for disease incidence and antibiotic treatment in the post-PCV era.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Shifts in pneumococcal serotypes following introduction of 7-valent pneumococcal conjugate vaccine (PCV-7) may alter the presence of other bacterial pathogens co-inhabiting the same nasopharyngeal niche. METHODOLOGY/PRINCIPAL FINDINGS: Nasopharyngeal prevalence rates of S. pneumoniae, S...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382588/

データ提供：米国国立医学図書館（NLM）

Long-Term Effects of Pneumococcal Conjugate Vaccine

The world of [research field] is constantly evolving, with new discoveries and insights emerging all the time. This study investigates the long-term effects of the 7-valent pneumococcal conjugate vaccine (PCV-7) on the nasopharyngeal carriage of various bacterial pathogens. The researchers conducted a [research method] and discovered that [main discovery]. This finding suggests that the introduction of PCV-7 may have significant implications for the nasopharyngeal microbiome and the potential for disease transmission.

The Shifting Landscape of Bacterial Carriage

This research highlights the dynamic nature of bacterial carriage in the nasopharynx, demonstrating that [specific results] were observed after the implementation of PCV-7. This dynamic landscape emphasizes the need for ongoing surveillance and monitoring to assess the impact of vaccination on the spread of bacterial pathogens.

Understanding the Impact of Vaccines on Microbial Communities

This study underscores the importance of understanding the complex interactions within the human microbiome and the impact of interventions like vaccination. By examining the long-term effects of PCV-7, we gain valuable insight into how vaccines can influence the composition and behavior of microbial communities in the human body.

Dr.Camel's Conclusion

This research reminds us that the world of microbiology is a vast desert, with intricate ecosystems thriving within our very bodies. As we explore the impact of vaccines on these microbial communities, we gain a deeper understanding of the delicate balance of life and the potential for interventions to shape the future of human health.

Date :
  1. Date Completed 2013-01-04
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

22761879

DOI: Digital Object Identifier

PMC3382588

Related Literature

Article Analysis
・Effects of pneumococcal conjugate vaccine
SNS
PICO Info
in preparation
Languages

English

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