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Safety of saxagliptin: rationale for and design of a series of postmarketing observational studies.

Author: ApterAndrea, BhullarHarshvinder, CarbonariDena M, CardilloSerena, EspositoDaina B, FortierKimberly, FreemanCristin P, HaynesKevin, HennessySean, HolickCrystal N, HorneLaura N, KimmelStephen E, Lo ReVincent, MargolisDavid, MingEileen E, RazzaghiHanieh, ReddyK Rajender, ReesePeter P, RoyJason, StromBrian L, Van StaaTjeerd-Pieter, Wood IvesJennifer

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A series of postmarketing studies are being conducted to examine the safety of saxagliptin in real-world settings. The studies will investigate the incidence of hospitalization with acute liver failure, acute kidney injury, severe hypersensitivity reactions, severe infections, and major cardiovascular events.
Paper Details　
Original Abstract of the Article :
PURPOSE: To describe the design and rationale of a series of postmarketing studies to examine the safety of saxagliptin, an oral dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes mellitus, in real-world settings. METHODS: We are conducting a series of retrospective cohort studie...See full text at original site
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引用元：
https://doi.org/10.1002/pds.3318

データ提供：米国国立医学図書館（NLM）

Saxagliptin: A Journey Through the Desert of Type 2 Diabetes Treatment

This research delves into the safety of saxagliptin, a medication used to treat type 2 diabetes. It's like navigating a vast desert landscape, seeking to understand the potential risks and benefits of a new medication. The researchers were like explorers, carefully mapping the terrain to ensure the safety of this medication. They conducted a series of post-marketing studies to evaluate the long-term effects of saxagliptin, gathering data from real-world clinical settings.

Saxagliptin: A Potential Oasis in the Desert of Type 2 Diabetes

This research aims to provide valuable insights into the safety profile of saxagliptin, offering reassurance to patients and healthcare providers. It's like finding a safe and reliable oasis in the desert, a place where individuals can find relief from their condition. The researchers are carefully analyzing the data to identify any potential risks associated with long-term saxagliptin use.

Navigating the Desert of Type 2 Diabetes Treatment

This research highlights the importance of continued monitoring and evaluation of medications, even after they are approved for use. It's like carefully navigating a desert, ensuring that the chosen path is safe and reliable. This research provides valuable data to guide decisions about medication use and to ensure the safety of patients with type 2 diabetes.

Dr.Camel's Conclusion

This research is a testament to the importance of ongoing research in the field of medicine. It's like a desert expedition, where careful observation and analysis are crucial to uncover hidden dangers and to ensure the safety of those navigating the landscape. This research provides valuable insights into the safety of saxagliptin, helping us find the safest and most effective paths for those living with type 2 diabetes.

Date :
  1. Date Completed 2013-04-08
  2. Date Revised 2016-11-25
Further Info :

Pubmed ID

22763953

DOI: Digital Object Identifier

10.1002/pds.3318

Related Literature

Article Analysis
・Side Effects of saxagliptin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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