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Metaxalone estimation in biological matrix using high-throughput LC-MS/MS bioanalytical method.
Author: GoswamiDipanjan, GuruleSanjay, KhurooArshad, MonifTausif, SahaArabinda, VatsPoonam
Original Abstract of the Article :
Metaxalone is a skeletal muscle relaxant, an approved drug for pain relief. Published bioanalytical methods lacked detailed stability evaluation in blood and plasma. An accurate, precise, high-throughput tandem mass spectroscopic method has been developed and validated. Following solid phase extract...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.jchromb.2012.05.034
データ提供:米国国立医学図書館(NLM)
Metaxalone Estimation in Biological Matrix: A Camel's Guide to Desert Medicine
In the vast and intricate world of [pharmacokinetics], understanding how drugs move through the body is crucial. This study develops a [high-throughput LC-MS/MS bioanalytical method] for estimating [metaxalone] in [biological matrix], like a camel carefully analyzing the sand and water sources in a desert oasis to ensure its survival. This method is designed to be [accurate, precise], and [high-throughput], which is like having a trusty compass and a map that helps you efficiently navigate the desert of drug analysis.
A Precise Compass for Metaxalone: A Camel's Perspective
This research provides a powerful tool for [measuring metaxalone levels] in [biological samples], which can be valuable for [monitoring drug efficacy] and [optimizing treatment regimens]. It's like having a precise compass that helps you stay on course and avoid getting lost in the desert of drug therapy. This method is particularly useful for [clinical studies] using [metaxalone], helping researchers to gather accurate data and make informed decisions.
The Importance of Desert Medicine: A Camel's Wisdom
This study underscores the importance of [precision and accuracy] in [drug analysis] and [pharmacokinetic studies]. It's a reminder that [reliable data] is crucial for [making informed decisions] about patient care. As we navigate the desert of health, let's make sure we have the right tools and knowledge to guide our journey safely and effectively.
Dr. Camel's Conclusion
This research contributes to the field of [pharmacokinetics] by providing a [reliable and efficient method] for [metaxalone analysis]. It's a testament to the power of scientific innovation in helping us understand and manage the complex world of drugs and the body. Let's keep exploring the desert of knowledge and finding new ways to improve our health and well-being!
Date :
- Date Completed 2012-11-05
- Date Revised 2013-08-26
Further Info :
Related Literature
English
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