[Comparison of the rate of maternal complications of nifedipine and nicardipine in cases of preterm labor: historical study on two consecutive periods].

Author: DeisS, HaddadB, KayemG, LaasE

Paper Details 
Original Abstract of the Article :
OBJECTIVES: Calcium channel blockers are the most frequently used tocolytics as first-line in France, frequently intravenously (nicardipine [Loxen(®)]). We would like to compare the side effects of intravenous nicardipine and oral nifedipine. MATERIALS AND METHODS: We performed a restrospective stu...See full text at original site
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引用元:
https://doi.org/10.1016/j.jgyn.2012.04.020

データ提供:米国国立医学図書館(NLM)

Nifedipine vs. Nicardipine for Preterm Labor: A Comparison of Tocolytics

The field of preterm labor, like a vast and treacherous desert, presents many challenges for physicians seeking to prevent premature birth. Calcium channel blockers are commonly used as tocolytics, drugs that delay labor, but their relative efficacy and safety profiles remain a subject of investigation. This study, like a camel caravan exploring a new route, compares the side effects of intravenous nicardipine and oral nifedipine in managing preterm labor.

Navigating the Desert of Preterm Labor: A Choice of Tocolytics

The study found that patients treated with intravenous nicardipine experienced significantly more side effects compared to those receiving oral nifedipine. While both medications were associated with similar rates of adverse events not related to the administration route, nifedipine led to lower blood pressure and a shorter hospital stay. These findings, like a compass guiding travelers through a desert, offer valuable insights into the relative advantages and disadvantages of these tocolytics.

A Safer Path Through the Desert: Choosing the Right Tocolytic

The study provides valuable information for physicians managing preterm labor, highlighting the potential benefits of oral nifedipine over intravenous nicardipine. This knowledge, like a well-worn path through a desert, can help physicians navigate the challenges of preterm labor and select the most appropriate tocolytic for their patients. By considering the relative safety profiles of these medications, physicians can make more informed decisions to improve the health and well-being of their patients.

Dr.Camel's Conclusion

This study provides valuable insights into the relative safety and efficacy of nifedipine and nicardipine for managing preterm labor. The findings, like a map guiding a caravan through a desert, suggest that oral nifedipine may be a safer and more convenient option for many patients, potentially leading to improved outcomes and reduced hospital stays.

Date :
  1. Date Completed 2013-03-25
  2. Date Revised 2014-08-12
Further Info :

Pubmed ID

22771075

DOI: Digital Object Identifier

10.1016/j.jgyn.2012.04.020

Related Literature

SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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